STUDY OBJECTIVE To ascertain reasons for non-compliance with faecal occult blood tests in colorectal cancer screening programmes. DESIGN A standard interview by a trained nurse of a random sample of those who declined screening. SETTING The Leicestershire town of Market Harborough, where most of the 25,000 population are served by a single general practice of 10 partners. PARTICIPANTS Alt...

BACKGROUND Effective methods are needed to collect fecal samples from children for large-scale microbiota studies. Stool collected on fecal occult blood test (FOBT) cards that can be mailed provides an effective solution; however, the quality of sequencing resulting from this method is unknown. The aim of this study is to compare microbiota metrics of 16S ribosomal RNA (rRNA) gene sequencing fr...

objective: occult hepatitis b infection is a form of hepatitis in which despite of absence of detectable hbsag, hbv-dna is present in peripheral blood of patients. this clinical form of b hepatitis creates some problems for the iranian blood transfusion services. therefore, the aim of this study was the evaluation of status of occult hepatitis b infection in the rafsanjanese blood donors. mate...

Colorectal cancer (CRC) is termed as a civilization disorder, with high incidence in Australia, NewZealand, Europe and US, with lower rates in Africa and Central Asia.Risk factors for CRC include genetic disorders, diet, red meat, smoking, alcohol and lack of exercise is associated with increased risk. Individuals with inflammatory bowel disease (IBD) have an increased risk of CRC.Genomic analy...

OBJECTIVES Precursors to 1/3 of colorectal cancer (CRC), serrated polyps have been under-detected by screening due to their inconspicuous, non-hemorrhagic, and proximal nature. A new multi-target stool DNA test (multi-target sDNA) shows high sensitivity for both CRC and advanced adenomas. Screen detection of serrated polyps by this approach requires further validation. We sought to assess and c...

Dear Editor, Small bowel bleeding accounts for 5% of all gastrointestinal bleeding cases. Vascular lesions of the gastrointestinal tract include hemangioma, telangiectasia, angiodysplasia and phlebectasia1 and they account for 5-10% of all benign neoplasms of the small bowel.2 The diagnosis of small bowel hemangioma is not easy and different modalities with different diagnostic accuracy could b...

Despite the recognized benefits of colorectal cancer (CRC) screening, uptake is still suboptimal in many countries. In addressing this issue, one important element that has not received sufficient attention population preference. Our review provides a comprehensive summary up-to-date evidence relative to topic. Four OVID databases were searched: Ovid MEDLINE® ALL, Biological Abstracts, CAB and ...