BACKGROUND Maternal uniparental disomy of chromosome 6 (upd(6)mat) is a rare finding and its clinical relevance is currently unclear. Based on clinical data from two new cases and patients from the literature, the pathogenetic significance of upd(6)mat is delineated. METHODS Own cases were molecularly characterized for isodisomic uniparental regions on chromosome 6. For further cases with upd...

A heterokaryon is a tissue type composed of cells containing genetically different nuclei. Although heterokaryosis is commonly found in nature, an understanding of the evolutionary implications of this phenomenon is largely lacking. Here, we use the filamentous ascomycete Neurospora tetrasperma to study the interplay between nuclei in heterokaryons across vegetative and sexual developmental sta...

The MAT-B1 and MAT-C1 ascites sublines of the 13762 rat mammary adenocarcinoma differ in morphology, agglutinability with concanavalin A, and xenotransplantability. Both cell lines contain a major mucin-type glycoprotein, but the MAT-C1 (xenotransplantable) subline contains a 3-fold-greater content of sialic acid on the glycoprotein than does the MAT-B1 (nonxenotransplantable) subline. The pres...

The distinct rhizomorphic mats formed by ectomycorrhizal Piloderma fungi are common features of the organic soil horizons of coniferous forests of the Pacific Northwest. These mats have been found to cover 25e40% of the forest floor in some Douglas-fir stands, and are associated with physical and biochemical properties that distinguish them from the surrounding non-mat soils. In this study, we ...

Our discovery that plasmids containing the Friedreich's ataxia (FRDA) expanded GAA.TTC sequence, which forms sticky DNA, are prone to form dimers compared with monomers in vivo is the basis of an intracellular assay in Escherichia coli for this unusual DNA conformation. Sticky DNA is a single long GAA.GAA.TTC triplex formed in plasmids harboring a pair of long GAA.TTC repeat tracts in the direc...

background: toxoplasma gondii is a zoonotic protozoan parasite found worldwide and responsi­ble for major economic losses in most classes of livestock. this study was aimed to deter­mine the prevalence of t. gondii infection in sheep, cattle and horses in urmia, north-west of iran, using mat. methods : blood samples of 276 livestock and 26 horses were collected from july 2009 till april 2010. t...

One of the basic assumptions of management accounting illustrate that costschanges has a significance Relationship with increasing and decreasing in the levelof activity, recently after being raised of sticky costs issue by Anderson and hiscolleagues this assumption was discussed. It means Increases in costs by increasingthe more activity level of reduction in costs is exchange for the reductio...

Recently, discovering local resources and utilizing them have been underway for the purpose to revitalize regional economies. The authors have conducted some activities for regional activation using historical materials such as old documents and maps. For these activities historians play an important role to discover and utilize local resources from historical materials. The cost of transferrin...