Acne vulgaris is one of the most prevalent inflammatory skin conditions found in late childhood and adolescence. Despite various studies, the etiology or pathogenesis of acne is still not well understood and a single, primary cause has not been identified. In the past several decades, various studies have indicated that patients with acne are under increased cutaneous and systemic oxidative str...

OBJECTIVE This study was carried out to assess the knowledge, concepts and perceptions of the youth towards Acne. METHODS This cross-sectional study included 700 students of both genders from all geographic areas in Riyadh, Kingdom of Saudi Arabia during the year 2001. They were asked to complete a self administered questionnaire that contained several items measuring different areas in there...

In 2003, an international committee of physicians and researchers in the field of acne, working together as the Global Alliance to Improve Outcomes in Acne, developed consensus guidelines for the treatment of acne. These guidelines were evidence based when possible but also included the extensive clinical experience of this group of international dermatologists. As a result of the evaluation of...

OBJECTIVE The purpose of this study was to assess the impact of acne on the quality of life. Its secondary objective was to assess the influence of gender of students and severity of symptoms on the quality of life. . METHODS A cross sectional study was conducted on 100 students at Sultan Qaboos University (SQU) (40 males and 60 females) diagnosed with acne who attended the Student Clinic dur...

Acne vulgaris is a multifactorial inflammatory skin disease. One of the pathogenic factors in acne is Propionibacterium acnes (P. acnes). Traditional treatment of acne lesions involves topical application of antibiotics with anti-bacterial and anti-inflammatory properties. However, a failure of this therapy is widely associated with emergence of resistant bacteria. Therefore, a search for alter...

There is no single malady which causes supplementary psychic disturbance and more general insecurity and feeling of inferiority than acne vulgaris with post inflammatory acne pigmentation marks does. It is strongly associated with depression and anxiety. In addition to individuals with little objective evidence acne with post inflammatory acne hyperpigmentation marks may endure severe subjectiv...

OBJECTIVE To determine if there are differences in the activity of 17beta-hydroxysteroid dehydrogenase and 5alpha-reductase (responsible for the production of testosterone and dihydrotestosterone, respectively) in sebaceous glands obtained from men and women with and without acne. DESIGN Single-center examination of androgen levels and sebaceous gland enzyme activity in a cohort of volunteers...

BACKGROUND In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence rates are considerably lower in nonwestern...

INTRODUCTION Ceramide-containing moisturizers may offer benefits as an adjunct to acne treatment. METHODS An expert panel of 11 Canadian dermatologists, including an international clinical scientist, used the following modified Delphi process: 1) A systematic literature review for acne treatment, dry skin, irritation, depletion of ceramides in acne, and benefits of moisturizers and ceramide-c...

Acne is a common complaint in the primary care clinics. It has not only physical implications but also psychological. This article discusses the epidemiology, pathophysiology, and criteria for making the diagnosis. It also discusses endocrine disorders that may be the cause of acne. Treatment and management are discussed by subtype. Acne mechanica or sports-related acne is also discussed.