Plasmacytoma is a plasma cell neoplasm that locally infiltrates a bone or spreads to extramedullary areas. A new World Health Organization criterion defines solitary plasmacytoma of bone as a localized bone tumor consisting of plasma cells identical to those seen in plasma cell myeloma, which is manifested as a solitary osteolytic lesion in a radiological evaluation. Primary tumors of the stern...

BACKGROUND: Malignant neoplasms with lesions of the chest are quite rare in sternum and range from 0.5 to 3.1% total number patients bone tumors all localizations. In this connection, there few publications describing tactics surgical treatment methods prosthetics formed defect. The present article describes a clinical case successful application an individual prosthesis manubrium G1 chondrosar...

Most repair of heart lesions and pectus deformity has been performed in adult patients using long incisions, sternal splits, excision of deformed cartilages, and sternal turnover operations that could result in poor cosmesis and chest growth in children because of sternal devascularization. We performed simultaneous pectus repair and atrial septal defect closure in 2 children using a short long...

Congenital sternal defects are rare deformities frequently associated with other anomalies of the chest wall and other organ systems. Although pectus excavatum, pectus carinatum, and cleft sternum can present as isolated deformity, in most cases they are associated with heart and inner organs anomalies and described as symptoms of syndromes like Marfan syndrome, Noonan syndrome, Poland anomaly,...

The sternum is derived from a pair of vertical mesenchymal bands, called sternal bars, that develop ventrolaterally in the body wall. Chondrification occurs in these bars craniocaudally in the median plane to produce cartilaginous models of the manubrium, body segments (sternebrae), and the xiphoid process. Fusion of the bars at the inferior end of the sternum is sometimes incomplete (1, 3). Th...

Removal of the whole sternum for malignant tumor results in a large defect, causing a severe deformity and possible paradoxial movement of the chest wall. Many of thoracoplasty cases after total sternectomy require considerably complicated invasion. Recently, we performed on a patient with chondrosarcoma of the sternum total resection of the sternum including bilateral costal cartilage followed...

Malignant bone tumors of the chest wall and sternum are more rare because most bone tumors occur in the long bones or joints.Osteosarcoma (OS) is a malignant bone tumor that occurs in the second or third decade of life. The men/women ratio is about 3:2 and half of the tumors occur near the knee. The most commonly occurring malignant tumor in sternum is chondrosarcoma and occurrence of osteosarc...

Introduction: Reconstruction of chest wall defects remains a very challenging issue and often requires prosthetic repair to prevent flail chest and paradoxical breathing. Case Report: We report a case of chest wall reconstruction following resection of a long standing, massive, well differentiated, primary chondrosarcoma of the sternum which was involving the entire body of sternum and adjoinin...

We report a very rare and successful surgery for primary malignant tumor of the sternum. A 73-year-old male, previously healthy, was admitted to our hospital because a chest computed tomography scan detected an abnormal shadow that suggested a sternal tumor destroying part of the sternum body. Aspiration needle biopsy demonstrated a primary sternal chondrosarcoma measuring 3 x 4 cm in diameter....

Skeletal shape varies widely across species as adaptation to specialized modes of feeding and locomotion, but how skeletal shape is established is unknown. An example of extreme diversity in the shape of a skeletal structure can be seen in the sternum, which varies considerably across species. Here we show that the Dchs1-Fat4 planar cell polarity pathway controls cell orientation in the early s...