We aim to construct quark hadron physics based on QCD. First, using lattice QCD, we study mass spectra of positive-parity and negative-parity baryons in the octet, the decuplet and the singlet representations of the SU(3) flavor. In particular, we consider the lightest negative-parity baryon, the Λ(1405), which can be an exotic hadron as theNK̄ molecular state or the flavor-singlet three-quark s...