We have examined the actions of histidine-specific reagents on potassium channels in squid giant axons. External application of 20-500 microM diethylpyrocarbonate (DEP) slowed the opening of potassium channels with little or no effect on closing rates. Sodium channels were not affected by these low external concentrations of DEP. Internal application of up to 2 mM DEP had no effect on potassium...

the steady state effect of vertical fins is assessed on a photovoltaic/thermal solar air heater having a double pass configuration in which fins are placed in the lower channel perpendicular to the direction ofair flow. air passes through the upper channel of the air heater and before passing in the opposite direction through the lower channel. the effects of design, climatic and operating para...

the capability of sand constitutive models is remarkably improved by taking into account the effect of soil state in their formulations. in this study, it has been shown that considering the effect of soil state leads to better simulation of soil instability of shear banding type. to this aim, constitutive equations of a state dependent sand model are explained first. consequently, the general ...

In this paper, we investigate problems of communication over physically degraded, state-dependent broadcast channels (BCs) with cooperating decoders. Two different setups are considered and their capacity regions are characterized. First, we study a setting in which one decoder can use a finite capacity link to send the other decoder information regarding the messages or the channel states. In ...

We propose a nonlinear filtering framework for approaching the problems of channel state tracking and spatiotemporal channel gain prediction in mobile wireless sensor networks, in a Bayesian setting. We assume that the wireless channel constitutes an observable (by the sensors/network nodes), spatiotemporal, conditionally Gaussian stochastic process, which is statistically dependent on a set of...

methadone is widely being used for opioid substitution therapy. however, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. this article is written to higlights th...

We have characterized the inward rectifying background potassium current, iK1, of canine cardiac Purkinje myocytes in terms of its reversal potential, voltage activation curve, and "steady-state" current-voltage relation. The latter parameter was defined from the difference current between holding currents in the presence and absence of 20 mM cesium. Our data suggest that iK1 rectification does...

The gating of ClC-0, the voltage-dependent Cl- channel from Torpedo electric organ, is strongly influenced by Cl- ions in the external solution. Raising external Cl- over the range 1-600 mM favors the fast-gating open state and disfavors the slow-gating inactivated state. Analysis of purified single ClC-0 channels reconstituted into planar lipid bilayers was used to identify the role of Cl- ion...