tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. it has broad spectrum activity, including staphylococcus aureus infections. this is the first study that evaluated the activity of tigecycline against staphylococcus aureus isolated from biological samples in iran. in vitro activity of tigecycline against 160 staphylococcus aureus including 99 methicil...

We report the complete genome sequence of the methicillin-sensitive Staphylococcus aureus (MSSA) strain FDA209P (ATCC 6538P and NCTC 7447).

S. aureus ID (bioMérieux, La Balme Les Grottes, France) is a new chromogenic agar medium designed to enable the isolation of staphylococci and the specific identification of Staphylococcus aureus. S. aureus produces green colonies on this medium due to production of alpha-glucosidase. To evaluate this medium, a total of 350 wound swabs were cultured onto S. aureus ID, CHROMagar Staph. aureus, a...

BACKGROUND Staphylococcus aureus alpha-toxin is a major virulence factor, but its mechanism of action in vivo is incompletely understood. METHODS We examined the role of alpha-toxin in S. aureus pneumonia using the mouse model of intranasal lung infection with S. aureus strain 8325-4 (hla(+) S. aureus) and an alpha-toxin-deficient mutant strain made on the 8325-4 background (hla(-) S. aureus)...

Chronic and recurrent bone infections occur frequently but have not been explained. Staphylococcus aureus (S. aureus) is often found among chronic and recurrent infections and may be responsible for such infections. One possible reason is that S. aureus can internalize and survive within host cells and by doing so, S. aureus can evade both host defense mechanisms and most conventional antibioti...

Tigecycline is a new glycylcycline antibiotic structurally similar to minocycline antibiotic. It has broad spectrum activity, including Staphylococcus aureus infections. This is the first study that evaluated the activity of Tigecycline against Staphylococcus aureus isolated from biological samples in Iran. In vitro activity of tigecycline against 160 Staphylococcus aureus including 99 methicil...

conclusions we report a high methicillin-resistant s. aureus rate in our hospital. additionally, t030 and t037 were the predominant spa-types among hospital-associated s. aureus. our findings emphasize the need for continuous surveillance to prevent the dissemination of multidrug resistance among different s. aureus protein a types in iran. background the incidence of nosocomial staphylococcus ...

background quorum sensing is a microbial cell-to-cell communication process. quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. gram-positive and gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. objectives the goal of this study was to assess the impact of subinhibitory concen...

PURPOSE OF REVIEW The present review describes the literature about the prevention of Staphylococcus aureus infections in surgery, published from August 2006 to January 2008, and puts it into perspective. RECENT FINDINGS To prevent Staphylococcus aureus infections after surgical procedures, three methods were described, that is, isolation precautions after methicillin-resistant Staphylococcus...

Severe Staphylococcus aureus (S. aureus) infections pose an immense threat to population health and constitute a great burden for the health care worldwide. Inter alia, S. aureus septic arthritis is a disease with high mortality and morbidity caused by destruction of the infected joints and systemic bone loss, osteoporosis. Toll-Like receptors (TLRs) are innate immune cell receptors recognizing...