Two factors are mainly responsible for the stability of the DNA double helix: base pairing between complementary strands and stacking between adjacent bases. By studying DNA molecules with solitary nicks and gaps we measure temperature and salt dependence of the stacking free energy of the DNA double helix. For the first time, DNA stacking parameters are obtained directly (without extrapolation...

In this paper, we investigate the method of stacked generalization in combining models derived from diierent subsets of a training dataset by a single learning algorithm, as well as diierent algorithms. The simplest way to combine predictions from competing models is majority vote, and the eeect of the sampling regime used to generate training subsets has already been studied in this context|wh...

Objectives: The purpose of this study was for evaluation of relationship between hand function and age, sex by Jebson Taylor Test.This study determined whether age might be a factor when associated with sex. Methods: In this study Jebson Taylor was evaluated on hand in 180 normal males and females (0.50% male, 0.50% female) in each of the following 7 subtest in 3 age groups: (15-25), (35-45)...

Abstract In this paper, I discuss a possibility for extending the nanosyntactic approach to case assignment and realization in order to model case stacking. Building on the work by Caha (2009), I show that nanosyntax can derive instances of overt case stacking as well as abstract case stacking. emain idea is that a case checking head can attract more than one K(ase)P. is leads to congurations ...

Few-layer graphene (FLG) has been predicted to exist in various crystallographic stacking sequences, which can strongly influence the material's electronic properties. We demonstrate an accurate and efficient method to characterize stacking order in FLG using the distinctive features of the Raman 2D-mode. Raman imaging allows us to visualize directly the spatial distribution of Bernal (ABA) and...

The spinodal decomposition of quenched polymer/solvent and liquid-crystal/solvent mixtures in a miniature Taylor-Couette cell has been simulated by molecular dynamics. Three stacking motifs, each reflecting the geometry and symmetry of the cell, are most abundant among the fully phase separated stationary states. At zero or low angular velocity of the inner cylindrical drum, the two segregated ...

The nucleosome core particle (NCP) is the basic building block of chromatin. Under the influence of multivalent cations, isolated mononucleosomes exhibit a rich phase behaviour forming various columnar phases with characteristic NCP-NCP stacking. NCP stacking is also a regular element of chromatin structure in vivo. Understanding the mechanism of nucleosome stacking and the conditions leading t...

As we enter the nanoscale regime, power reduction is of increasing importance, but the established leakage reduction techniques will become less effective. Subthreshold leakage is being joined by band-to-band tunneling and gate leakage as the primary leakage mechanisms. The increased significance of these leakage components threatens the usefulness of some traditional leakage reduction techniqu...

The crack propagation mechanism of Al0.1CoCrFeNi high-entropy alloy (HEA) was investigated with the molecular dynamics method. pre-crack and stretching processes single-crystal HEA grain boundaries were simulated. effects strain rates different crystal structures on therein at room temperature studied. They both exhibited plastic deformation ductile fracturing, tip involved dislocations 45° 135...

Oligopeptides containing tyrosyl, lysyl, and alanyl residues bind to polynucleotides and nucleic acids as shown by proton magnetic resonance, fluorescence spectroscopy, and difference absorption spectroscopy. Proton magnetic resonance data indicate that stacking of tyrosyl residues with nucleic acid bases takes place only in single-stranded structures (such as poly(A) or denatured DNA). Stackin...