background: rad51 is a protein with critical role in double strand break repair. down-regulation of this protein has a significant effect in radiosensitivity of some cell lines like prostate carcinoma. compared to monolayer cell culture model, the spheroids are more resistant to radiation. the aim of the current study was to determine the rad51 protein level in du145 spheroids, and monolayer ce...

background: the metabolically active tumor cells may be characterized by a pronounced adenosine release that regulates the growth and development of the tumor. consequently, the expression pattern of defined receptor subtypes will be an important determinant for specific effects of adenosine on the control of tumor cell growth. in recent studies, the expression profile, signal transduction, mol...

plant-based drugs are regarded promising recently. scrophularia has been shown various biological activities such as antimicrobial, antitumor and anti-inflammatory properties. according to pervious researches, bacteria are becoming resistant to some kinds of antibiotics, so it is prominent to find more reliable sources against them. here staphylococcus aureus as a common type of gram- positive ...

objective(s): this study was designed to indicate whether different fractions from artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress and apoptosis induced by doxorubicin (dox) in rat pheochromocytoma cell line (pc12). material and methods:cell viability was determined by mtt assay. also, activation of caspase-3 and superoxide dismutase were evaluated...

introduction: low level laser therapy (lllt) also known as photobiomodulation, is a treatment that uses low-level lasers or light-emitting diodes (leds) to change cellular function and is a clinically well accepted tool in regenerative medicine and dentistry. considering the variety of laser, exposure, cells and study types, the exact effects of low level laser therapy seems to be unclear. the ...

Background: Monoclonal antibodies (mAbs) are essential tools for many molecular im-munology investigations, epitope mapping and molecular modelling, clinical laboratory di-agnostic tests and immunotherapy. Humoral immune response of immunized animals largely depends on the nature of antigen and the immunization technique. Polysaccharides and heavily-glycosylated proteins are very elusive target...

Abstract Background and Aims: To identify and isolation of viruses a susceptible cell is need which can be primary or line. The use of primary cells is laborious, time consuming and expensive, while the use of cell lines is much easier and faster. IRKHBK cell line was originated from primary cells of bovine kidney by continuous passage. The aim of this study was to introduce the IRKHBK cell ...

the selection of high yielding varieties with good stability‏ ‏is an important objective in rice breeding ‎programs. the grain yield of eight rice lines with a check (nemat) were compared‎‏ ‏on six locations of gilan ‎and mazandaran provinces during two years, using rcbd with four replications. combined analysis of ‎variance showed that the effect of variety and year ‎‏×‏‎ location ‎‏×‏‎ variet...