Autofluorescence of rabbit and human epithelial tissues were studied by using a depth-resolved fluorescence spectroscopy system with multiple excitations. Keratinization was found to be common in the squamous epithelium. Strong keratin fluorescence with excitation and emission characteristics similar to collagen were observed in the topmost layer of the keratinized squamous epithelium. The kera...

Alveolar epithelial type II (AT2) cells secrete pulmonary surfactant via lamellar bodies (LBs). Abnormalities in LBs are associated with disorders, including fibrosis. However, high-content screening (HCS) for LB abnormalities is limited by the lack of understanding AT2 cell functions. In present study, we have developed harboring LB-like organelles that proteins. These were more similar to tha...

A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...

Eosinophilic esophagitis (EE) is an atopic condition of the esophagus that has become increasingly recognized over last decade. It associated with a variety esophageal symptoms such as dysphagia, food impaction and chest pain. predilection for white males between age 30 40 years age. EE diagnosed based on combination typical mucosal biopsies demonstrating squamous epithelial eosinophil-predomin...

Introduction: squamous odontogenic tumor is a rare benign locally infiltrative odontogenic tumor of epithelial origin and only a few cases, less than 50, have been reported in literature. the challenge is in diagnosing the tumor is due to its close resemblance to acanthomatous ameloblastoma and well differentiated squamous cell carcinoma. case report: Herein we report, not previously reported, ...

Mammalian esophagus exhibits a remarkable change in epithelial structure during the transition from embryo to adult. However, the molecular mechanisms of esophageal epithelial development are not well understood. Zebrafish (Danio rerio), a common model organism for vertebrate development and gene function, has not previously been characterized as a model system for esophageal epithelial develop...

p63 is the identity switch for uterine/vaginal epithelial cell fate, and disruption of p63 expression by diethylstilbestrol (DES) induces cervical/vaginal adenosis in mice. In this article, we report the expression patterns of p63 isoforms (TA, DeltaN, alpha, beta and gamma) in mice, focusing on the reproductive tract. We also present the reproductive tract phenotype of female p63-/- mice. Fina...

Ten UriSed 3 PRO automated microscopes (77 Elektronika, Hungary) were verified for nine HUSLAB laboratories with 160 000 annual urine samples. Particle counting of the primary instrument was against reference visual microscopy 463 specimens, and culture on chromogenic agar plates parallel 396 specimens. Nine secondary instruments compared pairwise instrument. Relative imprecisions to Poisson di...

The key features of malignant neoplasms are their local invasiveness and metastatic potential. Syndecan-1 - integral membrane heparan sulfate proteoglycan and cathepsins D and K - lysosomal proteases are important factors influencing different aspects of these processes. The study was undertaken to determine their expression in esophageal squamous cell carcinoma, and analyze relationship to sel...

Vulvar cancer is a rare tumor accounting for <5% of female genital tract tumors. The most common type vulvar malignancy squamous cell carcinoma. There are many histological variants carcinoma, keratinizing being the one. Sarcomatoid variant an extremely in vulva and comprises both epithelial mesenchymal features. Due to rarity this limited cases reported literature, no proper management guid...