Abstract Conventional radiographs and CT are primary investigations in spinal trauma. However MRI is the technique assessment of degenerative inflammatory disorders. There occasions when conventional radiographs, bone scintigraphy assist diagnosis A detailed understanding anatomy spine dynamic function essential interpretation imaging. Degenerative disorders including disc disease sometimes res...

OBJECTIVE Intracranial hypotension attributable to a spontaneous spinal cerebrospinal fluid (CSF) leak is an increasingly recognized cause of postural headaches. The cause of these leaks is poorly understood, but it is likely multifactorial and may involve a primary connective tissue disorder. We undertook a study to estimate the contribution of systemic connective tissue disorders to the devel...

objective: lumbar spinal canal stenosis (lscs) has prominent position in spinal disorders of the elderly. ligamentum flavum hypertrophy plays a dominant role in narrowing of the lscs. there are some clues that ligamentum flavum hypertrophy is associated with diabetes mellitus. our objective was comparison of histological properties of ligamentum flavum in lumbar spinal canal stenosis patients w...

All pathologic neuromuscular disorders have two common characteristics: (1) they occur as a direct result of damage to nervous tissue (supraspinal, spinal cord or peripheral nerve); and (2) the damage results in a disruption of a feedback loop or communication path between supraspinal structures (brain) or between supraspinal structures and the organs associated with them. These include four se...

In experiments on models of spinal injuries and spinal cord in 79 laboratory rats, we found changes in reflexes revealed by electromyographic evaluation of spinal cord function during the recovery process. It is established that the parameters of calf muscle reflex responses change immediately after spinal cord injury and that the severity of changes in motor responses in the late posttraumatic...

INTRODUCTION Clinical presentation of syringomyelia can mimic a variety of neuromuscular disorders. A misdiagnosis can result in progressive pressure on the spinal cord, causing the development of severe irreversible neurologic deficits. CASE PRESENTATION We report the very unusual case of a 50-year-old Latino man who developed severe distal muscle atrophy and bulbar dysfunction as a result o...

A 25-year-old man presented with subacute onset paraparesis with sphincter disturbance. His past medical history unvealed b-thalassemia intermedia (compound heterozygote IVS 1-5) and hereditary persistence of fetal hemoglobin type 2. His neurological examination disclosed a complete spinal cord syndrome without clear thoracic sensory level. Spinal cord imaging showed severe thoracic spinal sten...

The neuregulins are a family of polypeptide factors implicated in a wide range of neurological and psychiatric disorders including multiple sclerosis, schizophrenia, and Alzheimer's disease. Many alternatively-spliced forms of the NRG1 gene are released as soluble factors that can diffuse to near and distant sites within the nervous system where they can accumulate through binding to highly spe...