The distribution of immunoreactive dynorphin (ir-dynorphin) has been determined in dorsal and ventral aspects of spinal cord and in dorsal root ganglia of rabbit and rat. Concentrations are highest in dorsal root, with intermediate levels in ventral cord and low levels in dorsal root ganglia of both species. Levels of ir-dynorphin are relatively uniform over examined segments (vertebrae C2-S3) ...

Vertebral column resection is associated with a risk of spinal cord injury. In the present study, using a goat model, we aimed to investigate the relationship between changes in spinal cord volume and spinal cord injury due to spinal shortening, and to quantify the spinal cord volume per 1-mm height in order to clarify a safe limit for shortening. Vertebral column resection was performed at T10...

In order to study the spread of poliovirus in the spinal cord of bonnet monkeys, 10(8) TCID50 Mahoney strain of poliovirus was inoculated into the ulnar nerves of monkeys that were subsequently autopsied on days 1, 2, 3, 6, 9, 12, 14, 15 and 16 postinoculation (p.i.). Virus spread in the spinal cord, the accompanying histopathological changes and paralysis occurred in a cervico-thoraco-lumbar d...

These studies have demonstrated that ipsilateral renal artery occlusion (RAO) in rat results in the phosphorylation of cyclic AMP (cAMP) response element binding protein (p-CREB) in the thoracolumbar (T8-L2) spinal cord and associated dorsal root ganglia (DRG). p-CREB-immunoreactivity (IR) was expressed bilaterally in the thoracolumbar spinal cord, whereas expression in the DRG was ipsilateral ...

Spinal cord injury is a devastating chronic condition resulting in temporary or permanent motor,sensory or autonomic dysfunction of the cord. The manifestation of spinal cord injury based onthe severity and involved areas could be different. Numerous studies have demonstrated thatbradycardia, hypotension, and orthostatic hypotension are present insignificant number ofpat...

Local tetanus limited to one leg was studied in cats after intramuscular injection of tetanus toxin. 1. The electric and mechanical response of the affected muscle after a single stimulus to the intact sensory-motor nerve is greater in amplitude and duration than the response of the corresponding muscle of the unaffected leg (Fig. 1). 2. This augmented response of the muscle is associated with ...

Mitochondrial ATP synthase is the main enzyme of synthesis. A large number diseases, including neurodegenerative ones, are associated with disorders its assembly and functioning. The aim work to reveal patterns features regional distribution in neurons rat brain structures, a quantitative assessment content at cellular level. study was carried out on material from 5 outbred white male rats. Par...

a 60-year-old patient with testicular seminoma was referred for f-18 fdg pet/ct study to evaluate recurrence. in addition to hypermetabolic cervical, mediastinal and hilar lymph node tumoral metastases, segmental intense fdg uptake along the lumbar spinal cord suggestive of tumoral metastasis was noted which quite an unusual presentation is.  at the time of pet study the patient was symptomless...