background: neutrophil infiltration plays an important role in inflammatory reactions following spinal cord injury (sci) and these cells cause substantial secondary tissue damage. the purpose of this study was to determine the effect of oleuropein (oe) on myeloperoxidase (mpo) activity as an index of neutrophil infiltration. methods: rats were randomly divided into four groups of 7 rats each as...

a neurological disorder is any disorder of the nervous system is usually due to cell loss. the ultimate goal of cns therapy is to replace lost cells and tissue. there is no neuroprotective, pharmacological and effective treatment available that restores the injury-induced loss of function. recent studies suggest that identification of adult neural stem/progenitor cells indwelling in the neuroge...

spinal cord injury (sci) results in the damage of motor and sensory pathways. the molecular and cellular structure of the injury milieu has been shown to be vital for endogenous regeneration in most tissues. regeneration of injured central nervous system (cns) is limited by damaged cell environment. biomaterial scaffolds can reconstruct injured cns tissue following sci by promoting the migratio...

compound action potential (cap) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. these properties are measured using amplitude, latency and area under curve of caps recorded from spinal cord. here, the isolated spinal cord was set in a double sucrose gap (dsg) chamber and its response to intracellular stimulation ...

Rupp, Rüdiger, University Hospital Heidelberg, Spinal Cord Injury Center, Heidelberg, Germany Franz, Steffen, University Hospital Heidelberg, Spinal Cord Injury Center, Heidelberg, Germany Berberich, Monika, University Hospital Heidelberg, Spinal Cord Injury Center, Heidelberg, Germany Rohm Martin, University Hospital Heidelberg, Spinal Cord Injury Center, Heidelberg, Germany Eck, Ute, Universi...

background: studies have demonstrated the effect of different dietary fats on blood pressure (bp) in general population. however, these associations have not yet been described in people with spinal cord injury (sci). methods: referred patients to brain and sci research center between 2011 and 2014 have been invited to participate. only paraplegic individuals were recruited and patients with in...