PURPOSE Piroxicam, is non-steroidal anti-inflammatory and analgesic agent, which is widely used in the treatment of patients with rheumatologic disorders. A new analytical approach based on the dispersive liquid-liquid microextraction (DLLME) has been developed for the extraction and determination of PX in pharmaceutical preparation and human urine. METHODS From the PX standard solution or so...

A very simple, rapid and cost effective spectrophotometric method is described for the determination of isoxsuprine hydrochloride (ISX). The method is based on the selective reduction of Folin-Ciocalteu’s reagent (F-C reagent) by phenolic and amino group present in ISX in alkaline medium to form a blue coloured chromogen which absorbs maximally at 770 nm. Beer’s law is obeyed in the concentrati...

One of the biggest global public health issues, cancer has a negative impact on people's and quality life. Therefore, it is undeniable that interest in drugs for treatment increased. On other hand, addition to patient safety during administration used due their possible toxic properties, crucial maintain safe working environment safeguard professionals who provide from possibility coming into t...

This paper reports the determination of ulifloxacin (UFX) by terbium-sensitized fluorescence using a second-order scattering method. UFX and Tb(III) ion form a fluorescence complex in aqueous solution, and its maximum excitation and emission wavelengths are located at 273 and 545 nm, respectively. In optimum conditions, the relative intensity at 545 nm has a linear relationship to the concentra...

Active manipulation of cells, such as trapping, focusing, and isolation, is essential for various bioanalytical applications. Herein, we report a hybrid electrokinetic technique for manipulating mammalian cells in physiological fluids. This technique applies a combination of negative dielectrophoretic force and hydrodynamic drag force induced by electrohydrodynamics, which is effective in condu...

A technique for the speciation of selenomethylcysteine (SeMeCys), selenocystine (SeCys), selenite [Se(IV)] and selenomethionine (SeMet) was established in this paper using high-performance anion-exchange chromatography coupled with atomic fluorescence spectrometry (HPAEC-AFS). Analytes were separated on an AminoPac PA10 column and then digested by on-line ultraviolet (UV) irradiation, which des...

In this study, we have developed a label-free immunosensor with the variation of resonance frequency (Δf) of a quartz crystal microbalance (QCM) as readout signal for ultrasensitive detection of Ketamine (KT). An optimized strategy for immobilization of KT antibody on the surface of the QCM chip was implemented via the self-assembly modification of 3-mercaptopropionic acid, and then activated w...

The electroreduction behaviour and determination of cefoperazone using a hanging mercury drop electrode were investigated. Cyclic voltammograms of cefoperazone recorded in universal Britton-Robinson buffers pH 3-6 exhibited a single irreversible cathodic peak. The process was adsorption-controlled. Britton-Robinson buffer 0.04 M pH 4.0 was selected as a supporting electrolyte for quantitative p...

This paper presents a method for calculating a priori uncertainty intervals for plutonium interpretations by fission track analysis (FTA) of human urine samples. The derivations of the method are adaptable to estimating uncertainty intervals of analysis of single samples, based on calibration data obtained from multiple samples spiked over a range of concentration. The data used in last year’s ...