The integrity of healthy respiratory epithelium is maintained, at least in part, by trapping inhaled particles and microorganisms in a protective blanket of mucus which is transported towards the oropharynx by the coordinated action of the underlying ciliated cells. Ciliary dyskinesia is a recently recognised condition in which there is profound disturbance of this clearance mechanism because o...

An experiment was made to test the fertility of ram semen showing morphological abnormality due to exposure of the rams to high ambient temperature. Pyriform cells distinguishable by posterior constriction of the head, tailless sperm and an acrosomal cap abnormality were identified. Three groups of 20 Merino ewes were each mated to two rams which had been heated for four days, or for two days, ...

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase (PHGPx) is regarded as the major molecular target of selenodeficiency in rodents, accounting for most of the histopathological and structural abnormalities of testicular tissue and male germ cells. PHGPx exists as a cytosolic form, mitochondrial form, and nuclear form (nPHGPx) predominantly expressed in late spermatids and sperm...

Cyclosporine, tacrolimus, and sirolimus are commonly used in renal transplant recipients to prevent rejection. However, information for comparative effects of these agents on the male productive system is extremely limited and controversial. In a physiologically and clinically relevant rat model of unilateral nephrectomy, we demonstrated that long-term oral administration of both cyclosporine a...

© Translational Andrology and Urology. All rights reserved. Transl Androl Urol, 2016;5(S1) tau.amegroups.com this study. Their obesity-associated markers were measured, and semen parameters were analyzed. Also, seminal plasma and serum TC, TG, HDL and LDL and serum FFA levels were detected. Results: Seminal plasma and serum TG, TC and LDL levels were positively related to age. Serum TC, TG and ...

BACKGROUND The goals of the study are evaluation the effects of food deprivation and isolation situation as a social stress on fertility; and in the following, investigation of the improving effect of melatonin as an antioxidant component. MATERIALS AND METHODS In this experimental study, We investigated histopathological and serological effects of melatonin and social stress (food deprivatio...

Little is known about the effect on spermiogenesis induced by microcystin-leucine arginine (MC-LR), even though such data are very important to better elucidate reproductive health. In the current work, with the aid of nematode Caenorhabditis elegans (C. elegans) as an animal model, we investigated the defects on spermiogenesis induced by MC-LR. Our results showed that MC-LR exposure induced sp...

Bull’s fertility is highly important as it involves the fertilization of oocyte to produce a good, viable and genetically potential conceptus. Artificial insemination is the most widely used technique followed throughout the world, to increase numbers of genetically potential breeding bulls, offering many advantage over natural service. High quality semen is crucial for successful artificial in...

The effect of aflatoxin-contaminated corn on albino mice was investigated using the sperm morphology assay. Blood parameter levels including; total white blood cells (WBC), total red blood cells (RBC), packed cell volume (PCV), serum bilirubin (SB) and fasting blood sugar (FBS) were also determined in the tested mice. Test mice were exposed to aflatoxin-contaminated corn (contamination level of...

Abstract Introduction Microdeletions of the Y-chromosome (Yq) and karyotype abnormalities are frequent causes male factor infertility. Current AUA/EUA guidelines recommend obtaining Yq microdeletion analysis, karyotype, genetic counseling in men with non-obstructive azoospermia or severe oligospermia (<5 mil/mL). A recent retrospective cohort study suggests that microdeletions primarily ...