Rowell syndrome is comprised of erythema multiforme-like lesions in association with lupus erythematosus along serologies speckled antinuclear antibodies, positive rheumatoid factor, anti-La/ anti-Ro and the clinical finding chilblains.1 currently classified as a subtype chronic cutaneous erythematosus.2 The majority cases are seen women aged 20-70 years. ratio affected to men 8:1. Indian patie...

Background: Passive transfer of ANA and anti-SSA has been reported in patients with common variable immunodeficiency disorder who received intravenous immunoglobulin (IVIG). IVIG is also recommended to treat some special or life-threatening rheumatic diseases. Objectives: This study was aimed explore whether any extractable nuclear antibodies (ENAs) were transferred these therapy. Methods: prod...

Sera from patients with certain autoimmune diseases tht contained autoantibodies to nonhistone nuclear antigens were used as reagents in an indirect immunofluorescent study. The distribution of these nuclear antigens was determined in synchronized human B lymphoid cells. Autoantibodies to Sm antigen, nuclear ribonucleoprotein complex and SS-B antigen were used. Although all three nonhistone ant...