نتایج جستجو برای: specific ige
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Food protein induced enterocolitis syndrome (FPIES) is a food-related non-IgE-mediated gastrointestinal hypersensitivity disorder. Atypical FPIES is characterized by the presence of specific IgE for the causative food. The guidelines suggested for diagnostic oral food challenge in pediatric patients affected by suspected FPIES are different from the ones for children with IgE-mediated food alle...
The present study was conducted to learn whether the perinatal and environmental factors could influence the total and antigen-specific IgE levels in umbilical cord blood. Retrospective data were obtained from 173 mother-infant pairs. Total and specific (for children's food, wheat/grass and house dust mite-HDM) cord blood IgE levels were determined using the immunoassay test. The total cord blo...
The infection of CD4+ cells by HIV leads to the progressive destruction of CD4+ T lymphocytes and, after a severe reduction of CD4+ cells, to AIDS. The aim of the study was to investigate whether HIV-infected patients with CD4 cell counts <200 cells/µl can suffer from symptoms of IgE-mediated allergy, produce allergen-specific IgE antibody responses and show boosts of allergen-specific IgE prod...
Wheat omega-5 gliadin and a high m.w. glutenin subunit (HMW-glutenin) have been reported as major allergens in wheat-dependent exercise-induced anaphylaxis. A simultaneous detection of specific IgE to epitope sequences of both proteins is considered to be a reliable method for diagnosis of wheat-dependent exercise-induced anaphylaxis. However, the IgE-binding epitope of HMW-glutenin remains unk...
A couple of decades ago, the diagnostic search for cause blood eosinophilia concerned, mainly, three major allergic diseases (bronchial asthma, rhinitis, atopic dermatitis), or parasitic invasion. In recent years, more and complex clinical syndromes, from reactive (secondary) to eosinophilic leukemia are increasingly considered by doctors different specialties. The aim our work was present a ca...
OBJECTIVE To compare the prevalence of allergy to cockroaches (Blattella germanica and Periplaneta americana) in asthmatic and non-asthmatic children and to determine the degree of agreement between the skin prick test and serum specific IgE levels, as well as to establish the relationship between cockroach allergy and total IgE levels. METHODS A case-control study involving 76 asthmatic and ...
BACKGROUND Local tissue production of antigen-specific immunoglobulin E (IgE) has been shown in patients with allergic rhinitis and in patients with chronic rhinosinusitis (CRS) with nasal polyps. In allergic fungal rhinosinusitis (AFRS), specific IgE has been established in nasal lavage fluid and eosinophilic mucin. In this study, local production of antigen-specific IgE within sinus mucosa of...
the rapid decrease in free serum IgE levels was noticed [3, 4] . However, the impact of omalizumab on changes in allergen-specific IgE levels has so far not been investigated. In a recent issue of the International Archives of Allergy and Immunology , Mizuma et al. [5] were the first to report changes not only in the levels of total IgE but also of allergen-specific IgE. The authors retrospecti...
BACKGROUND Prevention of IgE-binding to cellular IgE-receptors by anti-IgE (Omalizumab) is clinically effective in allergic asthma, but limited by IgE threshold-levels. To overcome this limitation, we developed a single-use IgE immunoadsorber column (IgEnio). IgEnio is based on a recombinant, IgE-specific antibody fragment and can be used for the specific extracorporeal desorption of IgE. OBJ...
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