background previous studies provided inconsistent associations of smoking, stroke, and serious psychological distress (spd) with epilepsy while urban-rural differences in the associations of risk factors with epilepsy are not well documented. objectives this study aimed to evaluate the associations of lifestyle, health conditions, and spd with epilepsy and to examine whether the associations di...

Since polyamines (PAs) play a potential role in the regulation of growth and developmental processes in a wide variety of organisms, we have examined the influence of the PAs putrescine (Put) and spermidine (Spd) and the PA biosynthetic inhibitors alpha-difluoromethylornithine (DFMO), alpha-difluoromethylarginine (DFMA), methylglyoxal bis-(guanylhydrazone) (MGBG) and cyclohexylamine (CHA), sing...

BACKGROUND Co-exposure to cigarette smoke and alcohol leads to the generation of high concentrations of acetaldehyde and malondialdehyde in the lung. These aldehydes being highly electrophilic in nature react with biologically relevant proteins such as surfactant protein D (SPD) through a Schiff base reaction to generate SPD adducted malondialdehyde-acetaldehyde adduct (SPD-MAA) in mouse lung. ...

OBJECTIVE To present nationally representative findings on the prevalence, correlates, and comorbidity of and disability associated with DSM-IV schizotypal personality disorder (SPD). METHOD This study used the 2004-2005 Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions, which targeted a nationally representative sample of the adult civilian population of the United State...

INTRODUCTION In the past decade, the use of the Internet as a forum for communication has exponentially increased, and research indicates that excessive use is associated with psychiatric symptoms. The present study examined the rate of Internet use in adolescents with personality disorders, with a focus on schizotypal personality disorder (SPD), which is characterized by marked interpersonal d...

ackground: Structural abnormalities in prefrontal and cingulate gyrus regions—important in affective processing, impulse control nd cognition may contribute to the psychopathology of borderline personality disorder (BPD). Previous MRI studies examining olume have reported that compared with healthy controls, BPD patients have decreases in right anterior cingulate, no differences in orsolateral ...

In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39 to cysteine. Transcriptome comparison of the D39 wild-type grown at a restricted concentration of cysteine (0.03 mM) to one grown at a high concentration of cysteine (50 mM) in chemically-defined medium (CDM) revealed elevated expression of various genes/operons, i.e., spd-0150, metQ, spd-0431, metEF, gsh...

Hereditary elliptocytosis (HE) is a clinically and biochemically heterogenous group of diseases characterized by elliptically shaped erythrocytes and an autosomal dominant mode of inheritance. Whereas the self-association of spectrin heterodimers to tetramers is defective in a subpopulation of HE patients, designated HE[SpD-SpD], it is normal in others. We have examined the peptide pattern prod...

BACKGROUND The goal of the study was to examine mismatch negativity (MMN) in schizotypal personality disorder (SPD) individuals. Abnormal MMN has been a consistent finding in chronic schizophrenia and there also have been reports of reduced duration MMN in first episode schizophrenia patients [Umbricht, D., Krljes, S., Mismatch negativity in schizophrenia: a meta-analysis. Schizophrenia Researc...

We introduce and solve the Vehicle Routing Problem with Simultaneous Pick-ups and Deliveries and TwoDimensional Loading Constraints (2L-SPD). The 2L-SPD model covers cases where customers raise delivery and pick-up requests for transporting non-stackable rectangular items. 2L-SPD belongs to the class of composite routing-packing optimization problems. However, it is the first such problem to co...