نتایج جستجو برای: spastic

تعداد نتایج: 8978  

Journal: :Journal of neurology, neurosurgery, and psychiatry 2015
Takashi Tsuboi Hirohisa Watanabe Yasuhiro Tanaka Reiko Ohdake Noritaka Yoneyama Kazuhiro Hara Ryoichi Nakamura Hazuki Watanabe Jo Senda Naoki Atsuta Mizuki Ito Masaaki Hirayama Masahiko Yamamoto Yasushi Fujimoto Yasukazu Kajita Toshihiko Wakabayashi Gen Sobue

OBJECTIVES To elucidate the phenotypes and pathophysiology of speech and voice disorders in Parkinson's disease (PD) with subthalamic nucleus deep brain stimulation (STN-DBS). METHODS We conducted a cross-sectional study on 76 PD patients treated with bilateral STN-DBS (PD-DBS) and 33 medically treated PD patients (PD-Med). Speech and voice functions, electrode positions, motor function and c...

Journal: :Brain & development 2010
Carlo Fusco Daniele Frattini Enrico Farnetti Davide Nicoli Bruno Casali Francesco Fiorentino Andrea Nuccitelli Elvio Della Giustina

Mutations in the SPG3A gene (atlastin protein) cause approximately 10% of autosomal-dominant hereditary spastic paraplegia. Most patients with an SPG3A mutation present with a pure phenotype and early-onset disease, although complicated forms with peripheral neuropathy are also reported. We report a new heterozygous S398F mutation in exon 12 of the SPG3A gene causing a very early-onset spastic ...

Journal: :European journal of neurology 2001
J Rodda H K Graham

Classifications of gait and postural patterns in spastic hemiplegia and spastic diplegiía are presented, based on the work of previous authors. The classifications are used as a biomechanical basis, linking spasticity, musculoskeletal pathology in the lower limbs, and the appropriate intervention strategies. The choice of target muscles for spasticity management, the muscle contractures requiri...

Journal: :The Tohoku journal of experimental medicine 1988
I Tsuji R Nakamura

Tension lag time on electric stimulation (TLTe), i.e., latency from the stimulus to the rise of tension, and contraction time (CT) of the rectus femoris muscle on twitch contraction were measured on the affected and non-affected sides of eight patients with spastic hemiparesis due to stroke. Both TLTe and CT were significantly longer on the affected side than on the non-affected side, suggestin...

Journal: :Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics 2001
Y Ozawa O Shiromoto F Ishizaki T Watamori

Acoustic analysis was conducted to investigate symptomatic differences in decreased oral alternating motion rates (AMRs) between individuals with spastic and with ataxic dysarthria. The subjects were 6 individuals with spastic dysarthria, 6 with ataxic dysarthria and 6 normal speakers. Monosyllables /pa/ and /ta/ were used to examine alternating motions of the lips and tongue, respectively. In ...

2004
C J Shaw-Smith S J G Lewis E Reid

We present a family in which an initial clinical diagnosis of autosomal dominant pure hereditary spastic paraparesis (HSP) was made on the basis of a three generation pedigree in which both males and females presented with a spastic paraparesis. Subsequent biochemical and genetic analysis revealed that the family was in fact affected by the adrenomyeloneuropathy subtype of X-linked adrenoleukod...

Journal: :Journal of child neurology 2013
Rosemarie Rupps Juliette Hukin Martha Balicki Saadet Mercimek-Mahmutoglu Arndt Rolfs Cristina Dias

Hereditary spastic paraplegias and related genetically heterogeneous disorders may be difficult to distinguish clinically. The FA2H gene has been associated with autosomal recessive neurodegenerative phenotypes encompassing spastic paraplegia with or without dystonia, and demyelinating leukodystrophy. To date, few individuals with mutations in the FA2H gene have been described. We report a 5-ye...

Journal: :European Journal of Physical and Rehabilitation Medicine 2021

article: Muscle and tendon properties of the spastic lower leg after stroke defined by ultrasonography: a systematic review - European Journal Physical Rehabilitation Medicine 2021 August;57(4):495-510 Minerva Medica Journals

Journal: :Pediatric Neurology Briefs 2006

2014
Richard L. Lieber

Background: Cerebral palsy (CP) is an upper motor neuron disease that results in a progressive movement disorder. Secondary to the neurological insult, muscles from CP patients often become spastic. Spastic muscle is characterized by an increased resistance to stretch, but often develops the further complication of contracture which represents a prominent disability in children with CP. This st...

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