Growth in body size is a key life-history trait that has coevolved and interlinked with maturation, maximum age, mortality, generation time, the intrinsic rate of population growth. parameters are therefore required inputs majority assessment models used conservation or fisheries management. However, because difficulties involved proper aging individuals, growth unknown for vast species. Here, ...

PURPOSE A very high frequency of somatic mutations in the transforming growth factor-beta signaling component km23 has been reported in a small series of ovarian cancers (8 of 19, 42%). Functional studies showed that some mutations disrupt km23 function, resulting in aberrant transforming growth factor-beta signaling and presumably enhanced tumorigenicity. If verified, this would elevate mutati...