Less than 5% of patients with a plasma cell dyscrasia present with a single bone (SBP) or extramedullary plasmacytoma (EMP) without evidence of systemic disease (normocalcemia, absence of anemia, preservation of uninvolved immunoglobulins, or renal disease attributable to myeloma). Diagnosis requires biopsy confirmation of a monoclonal plasma cell infiltrate from a single site. The treatment of...

A 69-year-old woman was admitted with a three-week ;i` history of shortness of breath and wheezing accompanied by infrequent small haemoptyses. She had been treated at home for asthma with bronchodilators, and steroids, but had shown no improvement. She had stridor but no other added sounds in the chest. Systematic examination was normal. A blood 4 count and film were normal. ESR was 40 mm/min....