Surface solid dispersions using water-insoluble carriers like crospovidone, croscarmellose sodium, sodium starch glycolate, pre-gelatinized starch, potato starch and Avicel PH 101 were investigated to enhance the dissolution rate of the glimepiride, a poorly water insoluble drug. The effect of various carriers on dissolution profile was studied using presence absence model. The surface solid di...

Nanostructured Ni2As2O7 semiconductor samples were synthesized by a solid state method among As2O3 and Ni(NO3)2.6H2O raw materials at 650 °C (S1) and 750 °C (S2) as reaction temperatures. The synthesized nanomaterials were characterized by powder X-ray diffraction (PXRD) technique and F...

Nanostructured Ni2As2O7 semiconductor samples were synthesized by a solid state method among As2O3 and Ni(NO3)2.6H2O raw materials at 650 °C (S1) and 750 °C (S2) as reaction temperatures. The synthesized nanomaterials were characterized by powder X-ray diffraction (PXRD) technique and F...

INTRODUCTION The main objective of this study was preparation and characterization of solid dispersion of piroxicam to enhance its dissolution rate. METHODS Solid dispersion formulations with different carriers including crospovidone, microcrystalline cellulose, Elaeagnus angustifolia fruit powder, with different drug to carrier ratios were prepared employing cogrinding method. Dissolution st...

In this paper, we present a solid-core Silica-based photonic crystal fiber (PCF) composed of hexagonal lattice of air-holes and calculate the effective index and chromatic dispersion of PCF for different physical parameters using the empirical relations method (ERM). These results are compared with the data obtained from the conventional multipole method (MPM). Our simulation results reveal tha...

objectives: scaling and root planing (srp) is one of the most commonly used procedures during periodontal treatment. the aim of this study was to evaluate the root surface roughness after srp with erbium: yttrium aluminum garnet (er:yag) laser compared to ultrasonic and hand instruments.   materials and methods: in this experimental study, 56 extracted sound single-rooted teeth with moderate le...

background and objectives: bacillus species are attractive industrial organisms due to their rapid growth rates leading to a short fermentation cycle and for their capacity to secrete important enzymes and proteins such as xylanase into the extracellular medium. considering the industrial importance of xylanase, in this current study, bacillus spp. were isolated from different soils and were sc...

a simple, efficient and clean procedure has been developed for the cleavage of imines c=n bond. deprotection of imines to their parent carbonyl and amine compounds was achieved using p-toluenesulfonic acid in the solid state condition at 25-45 ˚c. the salient features of this methodology are shorter reaction times, cheap processing, high yields of product and easy availability of the catalyst. ...

The influence of preparation methodology of silymarin solid dispersions using a hydrophilic polymer on the dissolution performance of silymarin was investigated. Silymarin solid dispersions were prepared using HPMC E 15LV by kneading, spray drying and co-precipitation methods and characterized by FTIR, DSC, XRPD and SEM. Dissolution profiles were compared by statistical and model independent me...