نتایج جستجو برای: solid organ injury
تعداد نتایج: 593795 فیلتر نتایج به سال:
Immunotolerance, which is nonimmunologic reactivity to specific tissue, was demonstrated in animals in the 1950s. However, despite assiduous efforts, it has not been reproduced in human solid-organ transplant to date. Fortuitously, clinical operational tolerance, which is stable graft function for > 1 year with no immunosuppression, has been demonstrated, primarily in a few nonadherent recipien...
Abstract Tumour lysis syndrome (TLS) is a well-recognised oncological emergency caused by rapid destruction of cancer cells. Despite most commonly occurring in haematological malignancies or following initiation chemotherapy, rarely, it occurs solid tumours without any trigger. Release nucleic acids during cell breakdown produces large amounts uric acid resulting crystallisation within the rena...
Coccidioidomycosis is an endemic fungal infection of the southwestern United States. Normally a self-limited infection in healthy hosts, coccidioidomycosis can become a serious complication in patients who have had solid organ transplantation. Among patients whose solid organ transplantation was complicated by coccidioidomycosis, the infection has a variety of clinical presentations. Disseminat...
BACKGROUND To improve our understanding of risk factors, management, diagnosis, and outcomes associated with histoplasmosis after solid organ transplant (SOT), we report a large series of histoplasmosis occurring after SOT. METHODS All cases of histoplasmosis in SOT recipients diagnosed between 1 January 2003 and 31 December 2010 at 24 institutions were identified. Demographic, clinical, and ...
Organ transplantation has been the subject of ancient myths dating back to the twelfth century. The modern era of transplantation began in the early 1900s with the development of surgical techniques for constructing vascular anastomoses [ 1 ] leading to successful kidney transplantation in dogs in 1902 [ 2 ]. The fi rst series of human kidney transplants were performed in the Ukraine beginning ...
PURPOSE To explore the reproductive decision-making process with women who were organ transplant recipients (renal, lung, & heart transplants). STUDY DESIGN AND METHODS Grounded theory guided data collection and analyses. Mixed methods with audiotaped telephone interviews and a written survey measuring social support were used. As social support is critical for women who are organ transplant ...
The genus Nocardia includes more than 80 known species, with at least 33 of them related to human pathology [2,3]. It is an opportunistic pathogen, causing infection generally in immunosuppressed, mainly with long exposure to corticosteroids, transplanted or HIV positive patients. It has worldwide distribution and is very ubiquitous, being found in terrestrial and aquatic environments as well a...
1001 May 2013 A D VA N C E M E N T S in the field of anesthesia have led to significant improvements in our monitoring capabilities, safer anesthetic drugs, and improved pain control. Despite this remarkable progress, acute organ injury remains one of the leading causes for morbidity and mortality in surgical patients. Patients who require a major surgical intervention—such as cardiothoracic, v...
Active tuberculosis (TB) is one of the major opportunistic infections that may occur in solid organ transplant recipients. Diagnosis and treatment of latent and active TB are challenging in this population due to lack of randomized clinical trials. In this review, we discuss the clinical manifestations of TB, diagnosis of latent TB and treatment of both latent and active TB.
Damaris Vega & Khashayar Sakhaee† †Author for correspondence University of Texas Southwestern Medical Center, Department of Internal Medicine and, Charles & Jane Pak Center for Mineral Metabolism & Clinical Research, 5323 Harry Hines Boulevard, Dallas, TX 75390-8885, USA Tel.: +1 214 590 7783; Fax: +1 214 590 4091; khashayar.sakhaee@utsouth western.edu ‘Despite the introduction of new immunosup...
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