Buruli ulcer is a necrotizing infection of skin and soft tissue caused by Mycobacterium ulcerans that results in significant morbidity and often long-term disability. It is endemic in West and Central Africa affecting regions similarly burdened by a high prevalence of HIV. According to the Médecins Sans Frontières programme in Akonolinga, Cameroon, the prevalence of HIV is approximately three t...

changes and corresponding histopathology is unusual since the lesions had been observed already in the first years of life. Most patients with PXE-like PDE reported onset of disease after the fifth decade. Only one case in early middle age has been reported so far. Because of the late onset of the disease, some authors hypothesize PXE-PDE is related to intrinsic skin ageing and/or extrinsic age...

Marjolin’s ulcer is an uncommon malignant condition related to non-healing wounds, more often of burn injuries. Our aim is increase the suspicion index of primary care workers about the risk of squamous cell carcinoma in skin chronic ulcers or scar tissue, mainly in extremities. We report a Marjolin’s ulcer associated with traumatic chronic ulcer in the leg of a 73-year-old white female. Histol...

Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model. In order to elucidate the mechanism of this nerve damage, we tested and compared the cytotoxic effect of synthetic mycolactone A/B on cultured Schwann cells, f...

Copyright © 2009 Massachusetts Medical Society. A 52-year-old receptionist presents with an ulcer on her ankle that has persisted for a year. The use of narcotic analgesics once or twice a day and elevation of the leg reduce the pain. She does not have a history of diabetes and does not smoke. Physical examination reveals an ulcer, approximately 5 cm in diameter, above the medial malleolus. The...

Background: The most frequent and recurring type of leg ulcers seen in general practise is a venous ulcer (stasis ulcer). Its neglect has considerable negative influence on quality life, might result gangrene, may necessitate amputating the affected limb. serious incapacitating complication chronic insufficiency ulcer. conventional system medicine offers limited clinical evidence for its effect...

Sir, Pyoderma gangrenosum (PG) is a rare, destructive, inflammatory skin disease of unknown aetiology which belongs to the group of neutrophilic dermatoses (1 – 3). In about 50% of patients, an underlying disease will be found, such as inflammatory bowel disease and haematological malignancies. In others, the diagnosis of idiopathic PG is reluctantly made. We report here a case of PG associated...

The goal of this short communication is to report the uncommon presence of intracellular amastigotes of Leishmania in peritoneal fluid of a dog with leishmaniasis from Alagoas State, Brazil. Physical examination of an adult male rottweiler suspected to be suffering of leishmaniasis revealed severe loss of weight, ascitis, splenomegaly, moderately enlarged lymph nodes, onychogryphosis, generaliz...

OBJECTIVE To identify the nursing care prescribed for patients in risk for pressure ulcer (PU) and to compare those with the Nursing Interventions Classification (NIC) interventions. METHOD Cross mapping study conducted in a university hospital. The sample was composed of 219 adult patients hospitalized in clinical and surgical units. The inclusion criteria were: score ≤ 13 in the Braden Scal...

Aplasia cutis congenita (ACC) is a rare congenital defect in which localized or widespread areas of the skin are absent at birth. In the majority of cases, it is limited to the scalp especially on the vertex although other areas of the body may also be involved. Other congenital malformations can be associated with ACC. We present herein the case of a new born male with unilateral absence of sk...