We present three cases describing the various skin manifestations of presumed levamisole-contaminated cocaine use. Antibody-mediated vasculitis and neutropenia were consistent findings in these cases and repeat exposure resulted in distinct dermatologic complications. This phenomenon of levamisole-induced vasculitis and neutropenia is being increasingly described and has characteristic wound ma...

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with multi-system involvement and variable manifestations. There has been significant progress in TSC research and the development of technologies used to diagnose this disorder. As a result, individuals with mild TSC are now being diagnosed, including many older adults who have not developed seizures or cognitive abnormalities....

Before 1983 physicians diagnosed cat-scratch disease by its clinical manifestations and a positive Hanger-Rose skin test. Three out of four criteria, as outlined by Warwick, 1 were required for diagnosis. In 1983 Wear, et al.2 reported that they found gram-negative pleomorphic organisms using the Warthin-Starry stain on lymph nodes from patients with cat-scratch disease. The organism was then i...

clinical manifestations of sixteen children and teenagers exposed to chemical warfare in halabje are presented. 15 patients complained of burning of skin. dry coughing was present in 13 subjects. the most frequent signs were conjunctivitis, skin erythema, edema of the eyelids, hyperpigmentation, ulceration, erosion, dyspnea, closure ofthe eyes, blisters, edema of the skin, and crepitation in bo...

A 55-year-old man from the southwest United States (Tucson, AZ) presented with altered sensorium. He has a history of alcohol-induced liver cirrhosis. Family members reported thepatient had complainedof abdominal discomfort, watery nonbloody diarrhea, malaise, and leg discoloration earlier that day. He had not traveled outside of the United States for more than 20 years. Vitals were significant...

Three cases of gonorrhoea with pyrexia and lesions of the skin and joints (benign gonococcaemia) seen in one hospital group in 1969 within four months of one another are described. All three patients improved rapidly with penicillin therapy. This syndrome is commoner than is usually thought. It must therefore be borne in mind when a diagnosis is in doubt in a patient with unusual skin lesions a...

Two cases are reported illustrating a parallel course of extensive skin manifestations and lung cancer. The cases presented features of paraneoplastic acrokeratosis (Bazex's syndrome) and erythema gyratum repens though they did not completely correspond to these well-defined conditions. In both cases the cutaneous eruption appeared more than a year prior to the diagnosis of lung cancer, and the...

Inflammatory bowel disease (IBD) is a disease that affects the intestinal tract via an inflammatory process. Patients who suffer from IBD often have diseases that affect multiple other organ systems as well. These are called extraintestinal manifestations and can be just as, if not more debilitating than the intestinal inflammation itself. The skin is one of the most commonly affected organ sys...

In the practice of medicine, virtually every clinician encounters patients with skin disease. Physicians of all specialties face the daily task of determining the nature and clinical implication of dermatologic disease. In patients with skin eruptions and rashes, the physician must confront the question of whether the cutaneous process is confined to the skin, representing a pure dermatologic e...