Drug-induced toxic epidermal necrolysis (TEN) and acute cutaneous graft-versus-host reaction (GVHR) under immunopreventive therapy share some histopathological resemblance. So far, there are no serum biomarkers and no immunohistochemical criteria distinguishing with confidence and specificity the skin lesions of TEN and GVHR. Both diseases present as an inflammatory cell-poor necrotic reaction ...

Interest is rapidly developing in transcranial direct current stimulation (tDCS) as an emerging tool in neurology and psychiatry. tDCS involves the application of weak, unidirectional currents through scalp electrodes to alter neuronal excitability, that may outlast the period of stimulation (Arul-Anandam & Loo, 2009). In addition to being a tool for neurophysiological investigations, tDCS has ...

Background: Human fibroblasts are the part of the dermis that secrete extracellular matrix for the purpose of tissue repair. Culturing fibroblasts, which leads to formation of a monolayer of these cells, is used for treating various conditions including thermal burns and other skin defects such as diabetic and varicose vein leg ulcers. Therefore, we aimed at developing a fibroblast bank to acco...

Benign impetigo can progress into a potential fatal staphylococcal scalded skin syndrome (SSSS) if prompt diagnosis and correct therapy is not established rapidly. Local and systematic antibiotics as well as Lactulose are crucial in order to stop SSSS from progressing. Burns units should be involved when skin lesions are extensive.

Engineering of skin substitutes provides a prospective source of advanced therapies for treatment of acute and chronic skin wounds. Hypothetically, engineering of skin substitutes can allow deliberate fabrication of biologic materials with properties that address specific patho-biologic conditions (e.g., burns, scars, cutaneous ulcers, congenital anomalies). By design and incorporation of speci...

Due to the limited resources for the management of burns in most regions of Africa there is a significant role for many aspects of traditional African medicine. The active component of many traditional preparations is often of plant origin and more than 25 plants have been described as useful in relations to burns and wound healing. Carica papaya is currently used in The Gambia at the Royal Vic...