نتایج جستجو برای: single nucleotide poly morphism
تعداد نتایج: 1025175 فیلتر نتایج به سال:
There is a lot of information about genes sequence but their functions are still unknown. So, to fill the gap between structure and function of these sequences many reverse genetic researches have been done. Current experiment studying, how to design gene-specific primers, that can determine single nucleotide diversity and its impact on gene function.This research was condacted at International...
We present in this paper a systematic study on how to morph a well-trained neural network to a new one so that its network function can be completely preserved. We define this as network morphism in this research. After morphing a parent network, the child network is expected to inherit the knowledge from its parent network and also has the potential to continue growing into a more powerful one...
The single-stranded genomic RNA of Taura syndrome virus (TSV) is 10205 nucleotides in length, excluding the 3' poly(A) tail, and contains two large open reading frames (ORFs) that are separated by an intergenic region of 207 nucleotides. The ORFs are flanked by a 377 nucleotide 5' untranslated region (UTR) and a 226 nucleotide 3' UTR followed by a poly(A) tail. The predicted amino acid sequence...
the poly morphism of 4 micro satellite loci (bms1350, lgb, ilsts45, bms1915) associated with functional traits were evaluated for detecting the diversity level in baluchi breed of sheep. one hundred eighty five blood samples were collected from sheep herd in abbas-abad breeding station. dna extraction was performed using guanidinethiocyanate silica gel method. gene fragments of micro satellites...
BACKGROUND Single nucleotide polymorphism (SNP) arrays are important tools widely used for genotyping and copy number estimation. This technology utilizes the specific affinity of fragmented DNA for binding to surface-attached oligonucleotide DNA probes. We analyze the variability of the probe signals of Affymetrix GeneChip SNP arrays as a function of the probe sequence to identify relevant seq...
UML static models are expressed using a mixture of class diagrams and OCL expressions. In a well formed static model, the OCL expressions and class diagrams are type consistent. Checking for type consistency of static models involves both inclusion and parametric poly-morphism. This paper deenes a semantics of type consistency in terms of a type theory for UML static models. The type theory is ...
Both respiratory syncytial virus (RSV) and influenza A virus induce nucleotide/P2Y purinergic receptor-mediated impairment of alveolar fluid clearance (AFC), which contributes to formation of lung edema. Although genetically dissimilar, both viruses generate double-stranded RNA replication intermediates, which act as Toll-like receptor (TLR)-3 ligands. We hypothesized that double-stranded RNA/T...
Hybrid nucleotide-lipids containing locked nucleic acid (LNA) show enhanced hybridization properties with complementary single strand RNAs compared to DNA lipid analogues. The LNA adenosine lipid features unique binding properties with a high binding affinity for poly-uridine and the entropically driven formation of a stable complex (K(d) ≈ 43 nM). Enhanced hybridization properties of LNA-based...
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