نتایج جستجو برای: simvastatin smv
تعداد نتایج: 13579 فیلتر نتایج به سال:
Background and purpose: Today, implant treatment is one of the most popular dental treatments. To have a successful long-lasting implant treatment, enough bone is needed in that area. Given the positive effects of simvastatin on osteogenesis, this research aimed to compare the effect of freeze-dried bone allograft with and without simvastatin in extracted tooth socket in rats. Materials and me...
OBJECTIVES The purpose of this study was to assess the efficacy and safety of ezetimibe administered with simvastatin in patients with primary hypercholesterolemia. BACKGROUND Despite the availability of statins, many patients do not achieve lipid targets. Combination therapy with lipid-lowering agents that act via a complementary pathway may allow additional patients to achieve recommended c...
Background: The 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhi-bitors (statins) have revolutionized the treatment of hypercholesterolemia. Some evide-nce indicated the role of nodal refractoriness and concealed conduction in anticipating the ventricular rate during atrial fibrillation. Recent evidence has indicated that statins can reduce the incidence of both supraventricular a...
statins have antioxidant and anti-inflammatory effects that are not directly related to their cholesterol-lowering activity. this study aimed to investigate the effect of simvastatin on the extent of tissue damage in cisplatin-induced nephrotoxicity. simvastatin was orally given to rats in different doses (1, 2 and 4 mg/kg), 1 h prior to cisplatin injection (5 mg/kg, i.p.). all animals were dec...
Objective(s): Chemokines are wound mediators that promote angiogenesis during wound healing. We hypothesized that Simvastatin in combination with the bone marrow mesenchymal stromal cells (BMSCs) improve burn wound healing by ameliorating angiogenesis via SDF-1α/CXCR4 pathway.Materials and Methods: Under general anesthesia, deep partial-...
MicroRNAs (miRNAs) play key roles in a variety of cellular processes through regulation of their target gene expression. Accumulated experimental evidence has demonstrated that infections by viruses are associated with the altered expression profile of miRNAs and their mRNA targets in the host. However, the regulatory network of miRNA-mRNA interactions during viral infection remains largely unk...
A number of clinical and experimental studies have investigated the effect of simvastatin on bone regeneration. In the present study, the release of simvastatin from simvastatin-loaded calcium sulphate (CS) scaffolds and the effect of these scaffolds on osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs) in vitro and the effect of simvastatin locally applied from CS ...
Backgrounds: Type 2 diabetes mellitus is the most common metabolic disease and free fatty acids, as signaling molecules, can play a crucial role in the development of it. Different free fatty acids, through various cell membrane receptors, induce different effects on metabolic pathways and thereby affect insulin sensitivity. Simvastatin is a cholesterol decreasing drug prescrib...
در طول دو فصل زراعی 1379 و 1380، از مزارع سویای شمال کشور در استانهای مازندران و گلستان، نمونه های برگی مشکوک به ویروس موزائیک سویا (soybean mosaic virus=smv) جمع آوری گردیدند. نمونه های بذر سویا بدست آمده از این مناطق، جهت بررسی آلودگی به smv در گلخانه داخل گلدان کشت شدند. طیف وسیعی از علائم ویروسی در مزارع دیده شد بطوریکه تشخیص میزان آلودگی به smv مشکل بود. برای تشخیص ویروس از میزبانهای تکثیر...
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