This study aimed to investigate the role of miR-138 in human coronary artery endothelial cell (HCAEC) injury and inflammatory response and the involvement of the PI3K/Akt/eNOS signalling pathway. Oxidized low-density lipoprotein (OX-LDL)-induced HCAEC injury models were established and assigned to blank, miR-138 mimic, miR-138 inhibitor, LY294002 (an inhibitor of the PI3K/Akt/eNOS pathway), miR...

One of soil microbiology's most intriguing puzzles is how so many different bacterial species can coexist in small volumes of soil when competition theory predicts that less competitive species should decline and eventually disappear. We provide evidence supporting the theory that low pore connectivity caused by low water potential (and therefore low water content) increases the diversity of a ...

Dust samples collected annually for 5 years from 55 sites in southern Nevada and California provide the first regional source of information on modem rates of dust deposition, grain size, and mineralogical and chemical composition relative to climate and to type and lithology of dust source. The average silt and clay flux (rate of deposition) in southern Nevada and southeastern California range...

Significantly more occlusion bodies (OB) of DuPont viral construct HzSNPV-LqhIT2, expressing a scorpion toxin, were transported by artificial rainfall to cotton plants from sandy soil (70:15:15 sand-silt-clay) than from silt (15:70:15) and significantly more from silt than from clay (15:15:70). The amounts transported by 5 versus 50 mm of precipitation were the same, and transport was zero when...

MicroRNA (miR)-138 has previously been demonstrated to have a suppressive role in numerous types of human cancer, including non-small cell lung cancer (NSCLC). LIM domain kinase 1 (LIMK1) is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of cofilin. Previous studies have reported that LIMK1 is associated with NSCLC; however, the underlying reg...

BACKGROUND/AIMS The cases of bladder cancer (BC) with poor prognosis largely result from the distal metastases of the primary tumor. Since microRNAs (miRNAs) play critical roles during cancer metastases, determination of the involved miRNAs in the regulation of the metastases of BC may provide novel therapeutic targets for BC treatment. Here, we aimed to study the role of miR-138 in regulation ...

Artificial fill (Holocene)—Mud, sand, and gravel of varying proportions, possibly including foreign debris such as concrete, logs, timbers, or brick. Used for highway roadbeds and other construction. Thickness generally greater than 2 m. Mapped where fill substantially obscures or has altered original geologic deposit. Beach deposits (Holocene)—Soft sand, silt, and mud deposited or reworked by ...

Nonglacial deposits Artificial fill (Holocene)—Mud, sand, and gravel of varying proportions, possibly including foreign debris such as concrete, logs, timbers, or brick. Used for highway roadbeds and other construction. Thickness generally greater than 2 m. Mapped where fill substantially obscures or has altered original geologic deposit. Beach deposits (Holocene)—Soft sand, silt, and mud depos...

The 18-kDa cationic protein CAP18 is an antimicrobial protein isolated from rabbit granulocytes that binds lipopolysaccharide (LPS) and inhibits many of its biological activities. We covalently coupled a synthetic peptide representing amino acids 106 to 138 of CAP18 to human immunoglobulin G (IgG) by using the heterobifunctional linker N-succinimidyl-3-(2-pyridyidithio)propionate. The ability o...

The mineralogical investigation, geochemical analysis, and grain size calculation were carried out for floodplain sediment in the Tigris River to identify properties of sediment. average values three main classes, very fine sand, silt, clay are 9.67, 62.53 27.80%, respectively. silt fraction was predominant. classification nomenclature surface types from sandy-silt mud, they dominant Statistica...