Gold nanorods (AuNRs), rod-like gold nanoparticles, show strong plasmon bands in the near-infrared region, based on the longitudinal oscillation mode of surface plasmons. In this research, we have coated AuNRs with silica or poly (sodium 4-styrenesulfonate) (PSS) in order to evaluate the effects of surface modifications as a sensing probe material of AuNR. Multilayered assemblies of the PSS-coa...

Magnetic isolation of biological targets is in major demand in the biotechnology industry today. This study considers the interaction of four surface-modified magnetic micro- and nanoparticles with selected DNA fragments. Different surface modifications of nanomaghemite precursors were investigated: MAN37 (silica-coated), MAN127 (polyvinylpyrrolidone-coated), MAN158 (phosphate-coated), and MAN1...

Abstract Background Nanoparticles have been studied for brain imaging, diagnosis, and drug delivery owing to their versatile properties due small sizes. However, there are growing concerns that nanoparticles may exert toxic effects in the brain. In this study, we assessed direct nanotoxicity on microglia, resident macrophages of central nervous system, indirect toxicity neuronal cells exerted b...

a method was developed for removal, preconcentration and spectrophotometric determination of trace amounts of methyl red based on sio2-coated fe3o4magnetic nanoparticles. the influence of ph, dosage of adsorbent and contact time on the adsorption of dye was explored by central composite design. the kinetic data were analyzed based on the langmuir and freundlich adsorption isotherms. the langmui...

Perfluoroalkylsulfonic (PFS) and alkylsulfonic (AS) acid-functionalized magnetic nanoparticles were synthesized, characterized, and then evaluated for their ability to hydrolyze hemicelluloses. The magnetic core was made of cobalt spinel ferrite and was coated with silica to protect it from oxidation. The silanol groups allowed surface chemical modification of the nanoparticles with the PFS and...

The purpose of this study was the surface modification of nano MOF-5 (NMOF-5) or IRMOF-1 (Zn4O(C8H4O4)3) in order to prevent its rapid degradation in the phosphate-buffered saline (PBS), along with the simultaneous increase in its biocompatibility. The NMOF-5 sample was synthesized under the ultrasound irradiation and then it was loaded wit...

For controlled release and targeted delivery of curcumin in an aqueous medium a method of encapsulating curcumin and magnetic nanoparticles inside porous silica matrix has been developed. Curcumin and superparamagnetic nanoparticles are loaded inside porous silica in a single process. The graphic shows the TEM image of microtomed sample of Fe(3)O(4) particles surrounded by a silica matrix.

Mesoporous silica nanoparticles (MSNPs) have garnered a great deal of attention as potential carriers for therapeutic payloads. However, achieving triggered drug release from MSNPs in vivo has been challenging. Here, we describe the synthesis of stimulus-responsive polymer-coated MSNPs and the loading of therapeutics into both the core and shell domains. We characterize MSNP drug-eluting proper...

Introduction MRI is a high spatial resolution non-invasive technique but it has low specificity for targeting explicit pathologies. In an effort to improve specificity, MRI contrast agents with strong paramagnetic properties such as Gadolinium have been developed. However recent reports of suspected deaths associated with gadolinium administration have severely limited their use [1-2]. Iron oxi...