2921 Matrix analysis can provide powerful tools for solving related sequence design problems. For example, we have developed an iterative technique that can compute optimal signature sequence which satisfy additional constraints, such as unimodularity of the components [8]. Related methods can even construct maximum Welch-bound-equality sequences (MWBEs), which is a more challenging problem [21...

Motivation: Recent technological advances revealed that an unexpected large number of proteins interact with transcripts even if the RNA-binding domains are not annotated. We introduce catRAPID signature to identify ribonucleoproteins based on physico-chemical features instead of sequence similarity searches. The algorithm, trained on human proteins and tested on model organisms, calculates the...

MOTIVATION Recent technological advances revealed that an unexpected large number of proteins interact with transcripts even if they lack annotated RNA-binding domains. We introduce catRAPID signature to identify ribonucleo-proteins based on physico-chemical features instead of sequence similarity searchers. The algorithm, trained on human proteins and tested on model organisms, calculates the ...

Here, we report latent infections with Bartonella quintana and a hemotropic Mycoplasma sp. in a research colony of cynomolgus monkeys (Macaca fascicularis). Sequence alignments, evolutionary analysis, and signature nucleotide sequence motifs of the hemotropic Mycoplasma 16S rRNA and RNase P genes indicate the presence of a novel organism.

The complete nucleotide sequence of Tn10 has been determined. The dinucleotide signature and percent G+C of the sequence had no discontinuities, indicating that Tn10 constitutes a homogeneous unit. The new sequence contained three new open reading frames corresponding to a glutamate permease, repressors of heavy metal resistance operons, and a hypothetical protein in Bacillus subtilis. The glut...