نتایج جستجو برای: sibutramine

تعداد نتایج: 486  

Journal: :QJM : monthly journal of the Association of Physicians 2008
Y-Y Lin C-W Hsu S-J Chu S-H Tsai

Another dangerous combination for hypoglycemic coma: concurrent use of sibutramine and lorazepam Sir, With increasing demands to treat obesity in both medical and psychological aspects, many drugs are developed to lower human body weight. Those widely used anti-obesity drugs, such as olistat and sibutramine, are generally safe. But serious adverse effects could be developed when it is concurren...

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Journal: :Revista Brasileira de Psiquiatria 2011

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Journal: :International Journal of Obesity 1999

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Journal: :Clinical Psychopharmacology and Neuroscience 2013

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2012
Ji-Ah Kang Keimin Lee Kwang Min Lee Sukhee Cho Jinsoo Seo Eun-Mi Hur Chul-Seung Park Ja-Hyun Baik Se-Young Choi

The hypothalamus in the brain is the main center for appetite control and integrates signals from adipose tissue and the gastrointestinal tract. Antidepressants are known to modulate the activities of hypothalamic neurons and affect food intake, but the cellular and molecular mechanisms by which antidepressants modulate hypothalamic function remain unclear. Here we have investigated how hypotha...

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Journal: :European review for medical and pharmacological sciences 2011
D M Abo-Elmatty S A Zaitone

BACKGROUND AND OBJECTIVES Topiramate is newly approved as anticonvulsant that seems to promote body weight loss in humans. The present study was designed to evaluate the weight-controlling properties of topiramate in dietary obese female rats in comparison with sibutramine. MATERIALS AND METHODS Fifty rats were assigned as normal, high fat diet (HFD), HFD + sibutramine (7.5 mg/kg, p.o.), HFD ...

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Journal: :Obesity research 2003
Kristina Elfhag Stephan Rössner Anna Maria Carlsson Britta Barkeling

OBJECTIVE To study personality and clinical factors in weight loss by sibutramine (Meridia and Reductil), an anti-obesity drug enhancing satiety. RESEARCH METHODS AND PROCEDURES The subjects were 30 obese patients [43 +/- 12 years (mean +/- SD), BMI 40 +/- 4 kg/m(2)]. The treatment comprised 15 mg of sibutramine administered daily and monthly dietary advice. Weight loss after 6 months of trea...

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2010
Alfredo Halpern Renata B. Pepe Ana Paola Monegaglia Mônica Beyruti Maria Edna de Melo Marcio C. Mancini

Objective. To assess the efficacy and tolerability of the association sibutramine (10-20 mg/day) and orlistat (120 mg 2-3 times a day) in the treatment of obesity in a six-month open trial. Methods. 446 overweight and obese patients who sought treatment for obesity in a private clinic were assessed every 2 weeks during a period of 3 and 6 months. Results. After 3 months, the mean weight loss wa...

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Journal: :Health technology assessment 2012
R Ara L Blake L Gray M Hernández M Crowther A Dunkley F Warren R Jackson A Rees M Stevenson K Abrams N Cooper M Davies K Khunti A Sutton

BACKGROUND Obesity [defined as a body mass index (BMI) ≥ 30 kg/m(2)] represents a considerable public health problem and is associated with a significant range of comorbidities and an increased mortality risk. The primary aim of the management of obesity is to achieve weight reduction in the interests of health. For obese patients who cannot achieve or maintain a healthy weight by non-pharmacol...

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Journal: :Archives of internal medicine 2008
Karl Horvath Klaus Jeitler Ulrich Siering Anne K Stich Guido Skipka Thomas W Gratzer Andrea Siebenhofer

Weight loss is recommended in all major guidelines for antihypertensive therapy. We searched for randomized controlled trials investigating the effects of weight-reducing diets, pharmacologic substances, and invasive interventions for weight reduction on patient-relevant end points and blood pressure (BP) in patients with essential hypertension. No information on the effects on patient-relevant...

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