Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) system facilitates targeted genome editing in organisms. Despite high demand of this system, finding a reliable tool for the determination of specific target sites in large genomic data remained challenging. Here, we report SSFinder, a python script to perform high throughput detection of spec...

objective the diagnosis of de morsier syndrome or septo-optic dysplasia is made on the basis of the diagnosis of optic nerve hypoplasia. septo-optic dysplasia is defined by a variable combination of dysgenesis of midline brain structures including optic nerve hypoplasia and hypothalamic-pituitary dysfunction often associated with a wide variety of brain malformations of cortical development. th...

objective(s): there is controversial evidence about the effect of methamphetamine (meth) on spatial memory. we tested the time- dependent effects of meth on spatial short-term (working) and long-term (reference) memory in meth –sensitized and withdrawn rats in the morris water maze. materials and methods: rats were sensitized to meth (2 mg/kg, daily/5 days, sc). rats were trained in water maze ...

abstract aim and background: the key purpose of the study was to investigation the relationship of job burnout and some of job variables like type and level of responsibility, service and mangement experiences. method and materials: this descriptive study was conducted on 245 managers and vice-chancellors randomly selected by the cluster-sampling technique. they were assessed by job burnout que...

this study aimed to investigate the contribution of four common dfnb (“dfn” for deafness and “b” for autosomal resessive locus) loci and gjb2 gene mutations (exon 2) in hearing impairment in individuals living in markazi and qom provinces of iran. forty consanguineous iranian families with at least three affected individuals in family or pedigree who suffer from an autosomal recessive non-syndr...

We introduce and study the concept of $alpha $-semi short modules.Using this concept we extend some of the basic results of $alpha $-short modules to $alpha $-semi short modules.We observe that if $M$ is an $alpha $-semi short module then the dual perfect dimension of $M$ is $alpha $ or $alpha +1$.%In particular, if a semiprime ring $R$ is $alpha $-semi short as an $R$-module, then its Noetheri...