The platelet receptor for the von Willebrand factor (VWF) glycoprotein Ib-IX-V (GPIb-IX-V) complex mediates platelet adhesion at sites of vascular injury. The cytoplasmic tail of the GPIbalpha subunit interacts with the actin-binding protein, filamin, anchoring the receptor in the cytoskeleton. In motile cells, the second messenger phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) indu...

A pilot experiment was conducted by NSUOC and DLR in April-June 2008 in the Straits of Florida near Port Everglades, Florida in order to study the dynamics of far wakes of ships. In this experiment, a small boat with downward-looking sonar made “snake-like” sections through wakes of ships of opportunity during the TerraSAR-X overpasses. The ship identity and its parameters (length, speed, cours...

In-situ instruments were installed on 12 m high masts at the bow (bow mast) and the crow nest (middle of the ship, ship mast). The principal sensors installed on each mast were: CSAT-3 sonic anemometer and a CS7500 LiCor LI7500 open path H20/CO2 analyzer/hygrometer. The bulk meteorology sensors were mean temperature and humidity sensors in aspirator and 2-D sonic anemometers for mean wind. Data...

Local Vibrations represent one of the most critical parameters for the comfort evaluation on board of the ship. Normally a limit value of vibration is defined in the ship specification and the shipyard has the responsibility to assure that the specified values are not exceeded. Depending mainly on the extension, vibration phenomena could be divided in Global Hull vibrations and local vibrations...

In the past, Concept Exploration was the first step in defining the properties of a ship. Of the many ships studied during Concept Exploration, one was to be further developed and refined by the government during preliminary and contract design. Following award of the detail design and construction contract, a shipyard would complete the design and construct the ship. With the advent of Acquisi...

This article proposes a new collision avoidance decision method for ships, allowing ships at risk of collision to take timely collision avoidance measures to ensure safe passage. Through vessel traffic service (VTS) collision alert system, an analysis can be made for the probability of a ship collision and an early warning can be issued. For ships in potential collision danger, the proposed met...

The estimation of ship heading and speed from a high resolution Synthetic Aperture Radar (SAR) image of ship and its wake is important for monitoring and tracking ships. In order to get a correct and focused image of the moving ships, it is necessary to know the real positions and velocities of the ships. Though the ship can often be imaged clearly, its orientation may be difficult to estimate ...

v-Abl protein tyrosine kinase encoded by Abelson murine leukemia virus (Ab-MLV) transforms pre-B cells. Transformation requires the phosphatidylinositol 3-kinase (PI3K) pathway. This pathway is antagonized by SH2-containing inositol 5'-phosphatase (SHIP), raising the possibility that v-Abl modulates PI3K signaling through SHIP. Consistent with this, we show that v-Abl expression reduces levels ...

The paper presents design and realization of computer decision support system in collision situations of passage with greater quantity of met objects. The system was implemented into the real ship electro-navigational system onboard research and training ship m/v HORYZONT II. The radar system with Automatic Radar Plotting Aid constitutes a source of input data for algorithm determining safe tra...

After analyzing the existing simplified methods of ship-bridge collision and comparing their pros and cons, a relatively safe simplified analysis process is put forward. The time-history curve of the ship collision force obtained from the ship-rigid wall collision simulation using the software LS-DYNA is put into the whole bridge dynamic model in SAP2000 and then dynamic response analysis of th...