We experimentally probe the anisotropy of weakly vibrated flowing granular media. Depending on the driving parameters-flow rate and vibration strength-this anisotropy varies significantly. We show how the anisotropy collapses when plotted as a function of the driving stresses, uncovering a direct link between stresses and anisotropy. Moreover, our data suggest that for small anisotropies, the s...

The complete stress tensor has been measured using a computer simulation of an assemblage of rough, inelastic spheres in an imposed simple shear flow. Only five components of the stress tensor were found to be significantly different from zero. These represent the disperssive normal stresses 7,,, 7yy and 7,, and the in-the-shearplane shear stresses 7,y and 7yz; furthermore, the two off-diagonal...

Atherosclerosis is an inflammatory disease that preferentially forms at hemodynamically compromised regions of altered shear stress patterns. Endothelial cells (EC) and smooth muscle cells (SMC) undergo phenotypic modulation during atherosclerosis. An in vitro coculture model was developed to determine the role of hemodynamic regulation of EC and SMC phenotypes in coculture. Human ECs and SMCs ...

Web of plate girders in bridges are usually reinforced by welded transverse stiffeners inorder to improve their shear capacity. Due to problems associated with field welding and fatigue,welded stiffeners are not suitable for retrofitting existing bridges. Bolted stiffeners are a practicalalternative for strengthening girders that are expected to experience shear stresses in excess of theirdesig...

Endothelial cell alignment along the direction of laminar fluid flow is widely understood to be a defining morphological feature of vascular homeostasis. While the role of associated signaling and structural events have been well studied, associated intercellular stresses under laminar fluid shear have remained ill-defined and the role of these stresses in the alignment process has remained obs...

Human leukocytes retract pseudopods under normal physiologic levels of fluid shear stress even in the absence of any other mediator. To gain more detailed understanding of the mechanisms that regulate this cell behavior, we exposed leukocytes to a steady state laminar shear field in a flow chamber and computed the fluid stresses distribution on the surface of individual cells with and without p...

Interface stresses on a below-knee amputee residual limb during the stance phase of gait calculated using an analytical finite element model were compared with experimental interface stress measurements. The model was quasi-static and linear. Qualitatively, shapes of analytical and experimental interface stress waveforms were similar in that they were double-peaked with some distinct features a...

Thermal cycling is widely used as a qualification test in the microelectronic industry. This paper investigates an intriguing failure mode observed in such a test. Near the corners of a silicon die, shear stresses arise due to thermal expansion mismatch between the silicon and the packaging substrate. These shear stresses may have a small magnitude, being transmitted through packaging polymers,...

This study instituted a unique approach to bone tissue engineering by combining effects of mechanical stimulation in the form of fluid shear stresses and the presence of bone-like extracellular matrix (ECM) on osteodifferentiation. Rat marrow stromal cells (MSCs) harvested from bone marrow were cultured on titanium (Ti) fiber mesh discs for 12 days in a flow perfusion system to generate constru...