Previous studies determined that shear stress imposed on bovine aortic endothelial cell (BAEC) monolayers increased the hydraulic conductivity (L(P)); however, the mechanism by which shear stress increases L(P) remains unknown. This study tested the hypothesis that shear stress regulates paracellular transport by altering the expression and phosphorylation state of the tight junction protein oc...

Recent evidence suggests that circulating leukocytes respond to physiological levels of fluid shear stress. This study was designed to examine the shear stress response of individual leukocytes adhering passively to a glass surface. Human leukocytes were exposed to a step fluid shear stress with amplitude between 0.2 and 4 dyn/cm(2) and duration between 1 and 20 min. The response of the cells w...

We present a group of methods for decomposing an arbitrary 3D volume rotation into a sequence of simple shear (i.e., regular shift) operations. We explore different types of shear operations: 2D beam shear, a shear in one coordinate based on the other two coordinates; 2D slice shear, a shear of a volume slice (in two coordinates) according to the third coordinate; and 2D slice–beam shear, the c...

A compact-sized falling needle rheometer with quick operation and automatic flow analysis has been developed for viscometry of human blood. The volume of a sample of blood only needs to be 4 mL and the measuring time is within 3 min. Measured flow properties of blood are evaluated as a flow curve showing the relationship between the shear stress and shear rate. Observed flow curves of the human...

The design and construction of an apparatus for studying the simultaneous small angle neutron scattering (SANS) and steady shear viscosity behavior of polymer melts and concentrated solutions is discussed. Successful operation of the device is demonstrated on a blend of 20 weight percent deuterated polystyrene and 80 weight percent poly(vinylmethylether). The effects of shear on the critical be...

In this paper, we introduce and evaluate a novel sonoelastographic technique for imaging shear velocity distributions from propagating shear wave interference patterns (termed crawling waves). A mathematical relationship between local crawling wave spatial phase derivates and shear velocity is presented with phase derivatives estimated using an autocorrelation-based technique. Results from homo...

Self-assembled lamellar structures composed of block copolymers are simulated by molecular dynamics. The response of a bulk system to external shear is investigated, in particular, the average energy, the entropy production, and the stability of the lamellae's orientation. We distinguish two orientations, a parallel orientation in which the normal to the lamellae sheets lies in the direction of...

In this study, carbon nano fibers (CNFs) were mixed into epoxy resin through a magnetic stirrer and again mixed using ultra sonicator. Using hand layup technique, biaxial braided fiber composites were prepared with unfilled, 0.2, 0.5 and 1 wt% CNF. Tensile test and shear test was performed to identify the tensile strength and shear strength of the composites. Fractured surface of the tensile sp...

A trigonometric plate theory is assessed for the static bending analysis of plates resting on Winkler elastic foundation. The theory considers the effects of transverse shear and normal strains. The theory accounts for realistic variation of the transverse shear stress through the thickness and satisfies the traction free conditions at the top and bottom surfaces of the plate without using shea...

Adiabatic shear localization is a catastrophic failure mechanism which can occur in ductile metals under high strain rate loading. This mechanism is driven by a thermal instability process in which rapid temperature rise due to plastic work couples with thermal softening to cause uniform deformation to collapse into narrow bands of intense shear within which material ductility is exhausted. Adi...