BACKGROUND Recently another member of the paraoxonase gene family designated paraoxonase-2 has been identified. Paraoxonase-2 has antioxidant properties similar to paraoxonase-1 and paraoxonase-3. However, in contrast to paraoxonase-1 and paraoxonase-3, paraoxonase-2 is not associated with high-density lipoprotein and may only exert its antioxidant function at the cellular level. METHODS We a...

Osteoporosis is a common health concern in both developed and developing countries. In this study the association between anthropometric measures and osteoporosis was investigated in 3630 males and females visiting BMD clinic of Shariati Hospital, Tehran, Iran, a teaching hospital and referral center for osteoporosis affiliated to the Tehran University of Medical Sciences. Anthropometric measur...

BACKGROUND Liver cirrhosis has a significant impact on patient's quality of life and socioeconomic status and is associated with increased susceptibility to vehicle accidents and falls. OBJECTIVES This study was conducted to evaluate cognitive function in patients with cirrhosis. PATIENTS AND METHODS All subjects, who underwent transient elastography (TE) between March 2014 and August 2014 ...

Radionuclide imaging has the potential to be used in quantitative analysis of the regional function of organs. However, quantification of SPECT images is degraded by many factors such as Compton photon scattering. This could have a destructive effect on clinical reports so it is important to do scatter correction to get better quality SPECT images. We intended to determine how scatter correctio...

BACKGROUND Adenomyosis is a common benign disorder in pre-menopausal women that presents with uterine enlargement, pelvic pain, heavy menstrual bleeding, and dysmenorrhea. However, its risk factors have not been clearly determined. The aim of this study was to determine whether prior uterine surgery is a risk factor for adenomyosis. METHODS In this cross-sectional study, we reviewed the medic...

During the H1N1 (swine flu) pandemic of 2009, the World Health Organization (WHO) confirmed more than 14,000 deaths globally; this included a death toll of 147 in Iran. In order to evaluate (a) the appropriateness of the Oseltamivir dose through calculation of a patient’s creatinine clearance (CrCl) and (b) the quality of data in the medical charts, we conducted a retrospective study at the Sha...

Clostridium difficile is the most common cause of nosocomial diarrhea. It is usually a consequence of antibiotic treatment, But sporadic cases can occur. This study was aimed to determine the frequency of the nosocomial Clostridium difficile (C. difficile) associated diarrhea in Tehran University of Medical Sciences hospitals and study of antibacterial susceptibility of isolates. In this study ...

BACKGROUND Diabetes mellitus type II afflicts at least 2 million people in Iran. Neuropathy is one of the most common complications of diabetes and lowers the patient's quality of life. Since neuropathy often leads to ulceration and amputation, we have tried to elucidate the factors that can affect its progression. METHODS In this case-control study, 110 diabetic patients were selected from t...

INTRODUCTION Hepatitis C virus (HCV) infection is a hepatotropic virus causing a variety of extrahepatic immunological manifestations and is a risk factor of a variety of extrahepatic diseases, such as mixed cryoglobulinemia and membranoproliferative glomerulonephritis (MPGN), which is the most common glomerulonephritis. The aim of this study was to evaluate renal involvement in HCV-infected pa...

INTRODUCTION Bone marrow transplantation (BMT) is a major modality for malignant and hematologic disorders. This procedure is associated with a high morbidity and mortality such as acute kidney injury (AKI). Many factors, such as therapeutic agents, irradiation, and graft versus host disease (GVHD) can cause AKI. Bone marrow transplantation conditioning therapy in Iran is based on drugs such as...