Cigarette smoking is growing and nicotine is considered as the most adverse agent in the cigarette smoking. Nicotine is an alkaloid and forms 90% of alkaloids of cigarette. Nicotine is accountable for creating disorders and cancers such as lung cancer, heart disease and chronic lung disease. Nicotine can be considered as an autophagy and apoptosis inducer which can either directly or indirectly...

Cell specification requires that particular subsets of cells adopt unique expression patterns that ultimately define the fates of their descendants. In C. elegans, cell fate specification involves the combinatorial action of multiple signals that produce activation of a small number of "blastomere specification" factors. These initiate expression of gene regulatory networks that drive developme...

We study the European river Danube and the South American river Negro daily water levels. We present a fit for the Negro daily water level period and standard deviation. Unexpectedly, we discover that the river Negro and Danube are mirror rivers in the sense that the daily water levels fluctuations histograms are close to the BHP and reversed BHP, respectively.

There are many ways to avoid responsibility, for example, explaining what happens as the work of the gods, fate, society, or the system. For engineers, "technology" or "the organization" will serve this purpose quite well. We may distinguish at least nine (related) senses of "responsibility", the most important of which are: (a) responsibility-as-causation (the storm is responsible for flooding...

We apply combinatorial arguments to establish structural constraints on Costas arrays. We prove restrictions on when a Costas array can contain a large corner region whose entries are all 0. In particular, we prove a 2010 conjecture due to Russo, Erickson and Beard. We then constrain the vectors joining pairs of 1s in a Costas array by establishing a series of results on its number of “mirror p...

In this paper we test two hypotheses regarding magical thinking about the perceived likelihood of future events. The first is that people believe that those who “tempt fate” by failing to take necessary precautions are more likely to suffer negative outcomes. The second is the “protection effect”, where reminding people of precautions they have taken leads them to see related risks as less like...

Formation of the coronary vessels is a fundamental event in heart development. Congenital abnormalities in the coronary system can have major deleterious effects on heart function. It is also possible that subtle variation in the patterning of coronary vessels has significant but uncharacterized effects on myocardial structure and function. In addition, generation of the coronary vascular syste...