Metabolism of Anticancer Drugs: a Rapid and Specific Enzyme Immunoassay for Methotrexate NIGEL G. L. HARDING and A N N E P. SIMMONDS Department of Pathological Biochemistry, Royal Infirmary, Glasgow G4 OSF, Scotland, U. K. and GEORGE F. SHANKS Central Institute of Technology, Wellington, New Zealand and JOHN M. WHITELEY Department of Biochemistry, Scripps Clinic and Research Foundation, La Joll...

The use of inertial sensors for the gait event detection during a long-distance walking, for example, on different surfaces and with different walking patterns, is important to evaluate the human locomotion. Previous studies demonstrated that gyroscopes on the shank or foot are more reliable than accelerometers and magnetometers for the event detection in case of normal walking. However, these ...

This research aim was to determine the morphometric characteristics of native chickens in Huamual District. A total 300 adult Kampung (consisting 150 males and females) with more than 20 weeks age were used as samples. Analysis qualitative traits by calculating proportions or percentages, where grouped sex. Quantitative analyzed using descriptive statistical analysis mean, standard deviation, c...

When walking, step length provides critical information on traveled distance along the ongoing path [corrected] Little is known on the role that knowledge about body dimensions plays within this process. Here we directly addressed this question by evaluating whether changes in body proportions interfere with computation of traveled distance for targets located outside the reaching space. We stu...

objectives: knowledge about gender differences in intra-limb coordination during walking provides insight into the adaptability of central nervous system for controlling gait in older adults. we assessed the variability and phase dynamic of the intra-limb coordination in older men and women during walking. methods: twenty two older people, 11 female and 11 male, participated in this study. they...

A novel approach for estimating the instantaneous velocity of the pelvis during walking was developed based on Inertial Measurement Units (IMUs). The instantaneous velocity was modeled by the sum of a cyclical component, decomposed in the Medio-Lateral (ML), VerTical (VT) and Antero-Posterior (AP) directions, and the Average Progression Velocity (APV) over each gait cycle. The proposed method r...

Efforts to compare different surface marker configurations in 3-dimensional motion analysis are warranted as more complex and custom marker sets become more common. At the knee, different markers can been used to represent the proximal shank. Often, two anatomical markers are placed over the femoral condyles, with their midpoint defining both the distal thigh and proximal shank segment ends. Ho...

In order to generate a high ball speed in soccer, the inter-segmental coordination of the kicking leg is critical. The purpose of this study was to quantify the coordination between the thigh and shank movement in the sagittal plane during instep kicks. Eleven female soccer players were video recorded using a high-speed (80 Hz) video camera during penalty kicks. Hip, knee and ankle joint center...

The purpose of this study is to identify an effective method of support for the standing-up motion of children with cerebral palsy (CP). Experiments revealed remarkable differences in the shank and upper-body motions of children with CP compared with normally developed (ND) children. Shank tilt angles of CP children were smaller and their upper-body tilt angles were larger than those of ND chil...

The aim of the study was to evaluate the torque of the shank rotating muscles in patients with reconstructed anterior cruciate ligament (ACL) and rehabilitation accomplished in comparison with a control group. The study was carried out on the group of 187 males. For the purpose of the study a prototype testing device for the shank rotating muscles' torque under static conditions was used. The s...