INTRODUCTION Hypotension causes diffuse liver injury accompanied by increased local production of interleukin-6 (IL-6) in swine models of uncontrolled hemorrhagic shock (HS). IL-6 is transcriptionally up-regulated by nuclear factor (NF)-kappaB and results in activation of signal transducer and activator of transcription-3 (Stat3) in a murine model of controlled HS. Our objectives were: 1). to d...

The (pro)renin receptor [(P)RR] is implicated in organ pathology. We examined the cellular location of the (P)RR and whether a putative (P)RR antagonist, RILLKKMPSV, corresponding to the handle region of the prorenin prosegment (handle region peptide [HRP]) influences angiogenesis, inflammation, and neuronal and glial function in rat retina. The (P)RR was localized to retinal vessels, endotheli...

Left ventricular (LV) remodelling following myocardial infarction (MI) is associated with increased morbidity and mortality. Previous data suggest that angiotensin II (Ang II) plays a central role in the molecular events contributing to LV remodelling. We explored the effects of angiotensin-converting-enzyme (ACE) inhibition versus Ang II (AT(1)) receptor blockade on LV remodelling in mice post...

The author contends that sex differentials in childhood mortality in Pakistan are a likely outcome of son preference behavior by parents. Consideration is given to the historical improvement in the female disadvantage in mortality, the neglect of female children, gender and class factors, and son preference and high fertility. Data are from the 1981 Pakistan census and other official surveys....

Psychiatrist with a special interest in addiction. Born Gaza City, the Strip, occupied Palestinian territory, on June 20, 1954, he was killed by an air raid City May 16, 2021, aged 66 years. Although retired from his full-time work for Ministry of Health, Mouin Al-Aloul continued to as psychiatrist private practice. Like Ayman Al-Ouf, died when bomb destroyed home. studied medicine at Ain Shams...

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mystical language with its different kinds is the language that gnostics express their experiences, affections, eminent and deep mystical senses. the purpose of this article is to study the features of shams tabrizi’s mythical language. this study will make the reader more familiar with the language of mawlana and will lead him to a better understanding of mawlana’s instructions. it will also p...