A simplified method for the analysis of both the glyceride-rich Sf 20-1 O5 and the cholesterol-rich St 0-20 lowdensity lipoproteins is presented. It consists of serum lipoprotein fractionation by preparative ultracentrifugation and subsequent quantitative analysis by refractometry. Comparison of this technique with the technically more difficult analytic ultracentrifugal methodology reveals com...

This study was designed to assess changes in diet and serum lipoproteins in shift workers. Twelve shift workers and 13 day workers were examined before employment and after six months at work. Total cholesterol and serum triglycerides did not change significantly. In both groups a decrease in systolic blood pressure was observed. The ratio between apoB and apoA-1 lipoproteins increased by 18% i...

Cardiovascular diseases with an incidence of approximately 50% are the main causes of death in most advanced countries and an increasing trend in the developing world as well. The World Health Organization estimates that 12 million people per year worldwide die from cardiovascular diseases. Cardiovascular diseases are becoming an increasing problem worldwide and hypercholesterolemia has been co...

¯abstract backgrounds: lipoprotein (a) or lp(a) is a cholesterol-rich particle with atherothrombogenic properties. plasma level of lp(a) varies in different populations, however, little data on normal range of lp(a) lipoprotein among iranian population is available objective: the aim of this study was to estimate the normal range of lp(a) and also its relationship with other lipoproteins in a g...

introduction atherosclerosis is a disease which begins during childhood. oxidation of lipoproteins is an important factor implicated in atherosclerosis. vitamin c decreases blood serum lipids and may inhibit atherosclerosis. this study was designed to observe the effect of ascorbic acid on blood serum lipids in male rabbits fed high-cholesterol diet. methods twenty white male rabbits were weigh...

The push-pull solvatochromic pyrene derivatives PA and PK have been applied to the study of model membrane vesicles, cells purified human serum lipoproteins, using both confocal fluorescence microscopy spectroscopy. These polarity-sensitive probes provide information similar that obtained by Laurdan or Prodan, i.e. mainly lipid order in biomembranes, but they essential advantage being excitable...

The uptake, distribution, and exchange of chlorinated hydrocarbon insecticides (dieldrin and chlordecone) and biphenyls (2,4,5-2',4',5'-hexachlorobiphenyl and 3-chlorobiphenyl) among human lipoproteins was examined by fluorescence quenching, gel filtration, and ultrafiltration. The chlorinated hydrocarbons were rapidly taken up from solution or silica particles by lipoproteins. The distribution...