Background: The antioxidant defense in the pancreas is low because they are exposed to toxic substances daily. This study aimed to evaluate the ameliorating effect of Viola odorata flowers Extract (VOE) on the pancreas histology and function in Streptozotocin (STZ)-induced diabetic rats. Methods: Forty male rats were divided into five groups, consisting of controls; STZ; and STZ plus various d...

objective(s):the aim of this study was to evaluate, for the first time, whether the effects of low-dose adropin administration is effective in rats with hyperlipidemia. materials and methods: twenty one wistar albino female rats were randomly divided into 3 groups and fed with high-fat diet for 4 weeks to establish the hyperlipidemia model. meanwhile, adropin was administrated intraperitonealy ...

Objective(s): Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed to investigate the effects and mechanisms of magnesium supplementation on insulin receptor activity in elderly type 2 diabetes using a rat model and to provide experimental evidence for insulin resistance improvement by magn...

objectives: to investigate fasting glucose, glucose tolerance, insulin resistance and insulin–like growth factor 1 in patients with or without colorectal polyps. materials and methods: in this cross-sectional study, we evaluated fasting glucose, insulin, insulin–like growth factor 1 (igf-1), lipid profile and glucose tolerance test in 103 patients undergoing colonoscopy (52 normal and 53 with a...

background and objectives: the prevalence of diabetes mellitus (insulin resistance) in individuals with down's syndrome is more than healthy people, which is possibly because of the high prevalence of obesity among them. adiponectin is one of adipose tissue-secreted adipocytokines, which plays a role in pathogenesis of obesity and insulin resistance. this study was carried out with the aim of d...

Background: Serum insulin variations are occasionally observed in patients suffering infertility or gonad failure. The main purpose of the present study was to clarify the effects of gonadectomy and sex steroid hormone replacement on serum insulin level in rats. Materials and Methods: Male rats were divided into control, orchidectomized, and testosterone receiving orchidectomized animals. Femal...

background: chemerin is and adipokine produced and secreted by adipose tissue and is associated with functions such as insulin resistance, inflammation, and blood pressure regulation. the purpose of the present study was the determination of serum chemerin level in an iranian population with metabolic syndrome and its comparison with healthy individuals. materials and methods: the study subject...

due to the range of its constituents, colostrum has been considered as a supplement for various diverse purposes. this study was conducted to examine the effect of supplementary bovine colostrum on serum malondialdehyde (mda), antioxidant activity (aoa) and glucose in a diabetic rodent model. sixty male wistar rats were divided into 10 groups of six rats each for 40 days as follows: non-diabeti...

In order to investigate the relationship between insulin to glucagon ratio and metabolic factors in transitional period of dairy cows, 28 cows heifers with body condition score of 3.25- 3.75 were selected. Dairy cows received close up diet, from 21 days prepartum until parturition and lactation diet according to nutritional requirements after parturition. Blood was sampled at 10 days before and...

Paired serum and plasma samples from subjects were analyzed to determine if there was a difference in the insulin content of serum and plasma. Although there was no difference in the serum and plasma insulin concentrations in the samples as a group, there were differences in the serum and plasma insulin concentrations in individual subjects. Recovery of radioimmunoassayable insulin from clotted...