PURPOSE Serous ovarian carcinomas are the predominant epithelial ovarian cancer subtype and it has been widely believed that some or all of these may arise from precursors derived from the ovarian surface epithelium or fimbriae, although direct molecular evidence for this is limited. This study aimed to conduct copy number (CN) analysis using a series of benign and borderline serous ovarian tum...

Purpose: Serous ovarian carcinomas are the predominant epithelial ovarian cancer subtype and it has been widely believed that some or all of these may arise from precursors derived from the ovarian surface epithelium or fimbriae, although direct molecular evidence for this is limited. This study aimed to conduct copy number (CN) analysis using a series of benign and borderline serous ovarian tu...

PURPOSE Mitogen-activated protein kinase (MAPK) plays a pivotal role in signal transduction. Activation of MAPK is regulated by upstream kinases including KRAS and BRAF, which are frequently mutated in low-grade ovarian serous carcinoma. This study evaluates the expression of active MAPK in ovarian serous carcinomas, with response to treatment and survival. EXPERIMENTAL DESIGN Expression of a...

The main cause of the disease and death calves in early postembryonic period development is a feeding disorder. aim work was to analyze macro-and micromorphological changes digestive system calf with rennet rupture. To achieve this goal, standard microscopic research methods were used. Macroscopic examination revealed thickening, erosion mucous membrane esophageal gutter rollers, accumulation c...

Extraovarian papillary serous carcinoma of the peritoneum is a rare malignancy characterized by peritoneal carcinomatosis presenting with abdominal pain and ascites. This tumor is similar to serous ovarian carcinoma in context to its clinical presentation, histologic appearance, pattern of spread, treatment and prognosis. We hereby report two cases of extraovarian papillary serous carcinoma of ...

Macrocystic serous cystadenoma is an unusual and essentially benign pancreatic tumor. Herein, we report on a 40-year-old woman diagnosed with macrocystic serous cystadenoma who presented with obstructive jaundice. A cystic lesion in the head and body of the pancreas was revealed by abdominal computed tomography. Intraoperative pancreatic cyst aspiration ruled out mucinous cystic neoplasm which ...

INTRODUCTION Psammocarcinoma of ovary is a rare serous neoplasm characterized by extensive formation of psammoma bodies, invasion of ovarian stroma, peritoneum or intraperitoneal viscera, and moderate cytological atypia. Extensive medlar search showed presence of only 28 cases of psammocarcinoma of ovary reported till date. CASE PRESENTATION We herein report a case of psammocarcinoma of ovary...

currently, laparoscopic cystectomy is the first-line therapy for ovarian benign cysts that are resistant to current therapies. there are different studies that point to ovarian reserve damage due to laparoscopic cystectomy. in this study, we evaluate the ovarian damage following laparoscopic cystectomy for non-endometriosis cysts using ultrasound and pathology findings. this is a prospective co...

Immunohistochemical staining, with a monoclonal antibody specific for cytokeratins 5, 6, 8, 17 and 19 of dog submandibular, sublingual, parotid, palatine, tongue and zygomatic salivary glands resulted in staining of myoepithelial cells, duct epithelial cells (including intercalated, striated and secretory ducts) and some acinar epithelial cells. Differences in acinar staining between glands ref...

Exosome-encapsulated microRNAs have been recognized as novel and stable biomarkers for cancer. However, little is known about the role of exosomal microRNAs in colon cancer. In the present study, we investigated the expression of serous exosomal microRNA-638 (miR-638) and its prognostic effect in patients with colon cancer. Serous exosomal samples were assayed by quantitative real-time PCR. Kap...