The novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has introduced as causative agent for coronavirus disease 2019 (COVID-19) since the 2019 December. Human coronaviruses are classified in Nidovirales order and Coronavirdiae family. This family includes four genera. The SARS-CoV-2 is a member of Betacoronavirus genera and Sarbecovirus linage (linage B). There is ...

BACKGROUND AND OBJECTIVE Serological screening enables us to detect patients of celiac disease (CD) before they develop serious complications. This study was planned to assess the prevalence of CD in the family members of index cases by serological screening. PATIENTS AND METHODS A prospective study was conducted on 50 children diagnosed to be having CD. Serological screening of the family me...

Klassevirus is a proposed new genus of picornavirus that has been associated with pediatric diarrhea. In this study, we used recombinant klassevirus 3C protease as the capture antigen for an indirect serological enzyme-linked immunosorbent assay (ELISA). Four of six klassevirus reverse transcription (RT)-PCR-positive individuals demonstrated seroconversion against the 3C protease, suggesting th...

Background Evaluation of serological assays for hepatitis C (HCV) antibody screening is crucial ,as supplemental testing [Nucleic Acid Testing & Recombinant Immunoblot Assay (RIBA)] to verify anti-HCV reactive results is not widely practiced, due to limited availability and high cost. The current study was undertaken from January to May 2011, to evaluate 4 serological assays for HCV diagnosis, ...

BACKGROUND During the Dutch Q fever epidemic more than 4,000 Q fever cases were notified. This provided logistical challenges for the organisation of serological follow-up, which is considered mandatory for early detection of chronic infection. The aim of this study was to investigate the proportion of acute Q fever patients that received serological follow-up, and to identify regional differen...

The main aim of this study was to find a suitable rabies vaccination protocol which would allow usage of lower volumes of vaccine, fewer clinical visits and above all, enough serological effectiveness for high-risk individuals requiring pre-exposure immunization. Human diploid cell rabies vaccine was administered intradermally and intramuscularly in 60 previously unvaccinated volunteers, aged 1...

This study was conducted to determine the prevalence of Salmonellae contamination of chicken carcasses in slaughterhouses in central Iran (Yazd province). 435 samples were obtained from liver, breast— before and after chilling—and bacteriological and serological examinations were done. The results showed that the rate of contamination of liver, breast meat—before and after chiller—were 8.1, 18....

detection of plasmodium vivax specific antibodies with serological tests could be a valuable tool for epidemiological researches. whereas p. vivax cannot be simply obtained in vitro, serological tests using total or semi-purified antigens are infrequently used. given this restriction, the present study investigated whether recombinant p. vivax merozoite surface protein 1 (pvmsp-1 42 kda) could ...