Synchronous VLSI design is approaching a critical point, with clock distribution becoming an increasingly costly and complicated issue and power consumption rapidly emerging as a major concern. The last decade has witnessed a resurgence of interest in asynchronous logic which promises to liberate digital design from the inherent problems of synchronous systems. This activity has revealed a need...

the problems of sequential change-point have several important applications in quality control, signal processing, and failure detection in industry and finance. we discuss a bayesian approach in the context of statistical process control: at an unknown time $tau$, the process behavior changes and the distribution of the data changes from p0 to p1. two cases are considered: (i) p0 and p1 are fu...

In this paper, we propose a new approach to formal synthesis which focuses on the generation of verification-friendly circuits. Starting from a high-level implementation description, which may result from the application of usual scheduling and allocation algorithms, hardware is automatically synthesized. The target architecture is based on handshake processes, modules which communicate by a si...

Several methods have been proposed for synthesizing communication protocol specifications starting from given service specifications. Due to the inherently sequential nature of a finite state machine (FSM), some FSM-based protocol synthesis methods assume that primitives in the service specifications cannot be executed simultaneously. However, other synthesis methods were introduced to handle c...

In this work, we investigate optimality principles behind synthesis strategies for protein complexes using a dynamic optimization approach. We show that the cellular capacity of protein synthesis has a strong influence on optimal synthesis strategies reaching from a simultaneous to a sequential synthesis of the subunits of a protein complex. Sequential synthesis is preferred if protein synthesi...

The synthesis of fluorinated dual-responsive block terpolymers via sequential reversible addition–fragmentation chain transfer (RAFT) polymerization is presented.

A convenient, one-pot method for the synthesis of diazonium salt has been developed by the sequential diazotization of aromatic amines with NaNO2, polymer- supported periodic acid (PPIA) and 2-naphthole under solvent-free conditions at room temperature. By using this method, several types of aromatic amine, containing electron-withdrawing and electron-donating groups, were rapidly converted to ...

Abstract Background: The approach to vascular access in children with CHD is a complex decision-making process that may have long-term implications. To date, evidence-based recommendations not been established inform this process. Methods: RAND/UCLA Appropriateness Method was used develop miniMAGIC, including sequential phases: definition of scope and key terms; information synthesis literature...

This paper presents a sequential two-stage strategy for the stochastic synthesis of chemical processes in which flexibility and ability to adjust manipulated variables are taken into account. In the first stage, the optimal flexible structure and optimal oversizing of the process units are determined in order to assure feasibility of design for a fixed degree of flexibility. The feasibility is ...