Herpes simplex virus type 1 (HSV-1) and HSV-2 cause very similar acute infections but differ in their abilities to reactivate from trigeminal and dorsal root ganglia. To investigate differences in patterns of viral infection, we colabeled murine sensory ganglia for evidence of HSV infection and for the sensory neuron marker A5 or KH10. During acute infection, 7 to 10% of HSV-1 or HSV-2 antigen-...

Herpes simplex virus (HSV) latency in sensory ganglion neurons is well documented, but the existence of extraneuronal corneal latency is less well defined. To investigate the possibility of extraneuronal latency during ocular HSV infection, corneal specimens from 18 patients with quiescent herpes simplex keratitis (HSK) were obtained at the time of keratoplasty. Polymerase chain reaction (PCR) ...

Background & Aims: Lower limbs’ nerves are exposed to mechanical injuries in athletes (e.g. football players), because of the excessive physical demand of their job. The objective of the present study was to evaluate the influence of regular and intense sports, such as football, on nerves in the lower leg. This study was conducted during 2006 to 2007 in the Shiraz Rehabilitation Faculty, Univer...

Centrifugal ("antidromic") discharges in cat sensory fibers are observed consistently in a variety of experimental preparations and with many different surgical and recording techniques. As is well known, they can be either "spontaneous" or induced by afferent volleys in other sensory fibers. In addition, it is shown here that they can be elicited by antidromic motoneuron activation when the la...

This study was done to assess the percentage of abnormality in additional nerve conduction techniques after normal median distal latency (routine) in mild carpal tunnel syndrome (CTS). Bilateral nerve conduction studies were carried out in 116 consecutive symptomatic CTS patients (153 hands). Mild cases were based on normal routine (< 3.7 ms, peak-measured, 14 cm) and at least one technique abn...

The upper limbs of 10 healthy subjects were cooled and then warmed over physiological temperature ranges. The compound action potentials of median digital nerves, median sensory nerve at the wrist, radial sensory nerve at the wrist, and median thenar muscle, all showed progressive reduction in latency, amplitude, duration and area during rising temperature. Our studies suggest that the sensory ...

Learning in the marine mollusk Aplysia has been associated with enhanced sensory function, expressed in mechanosensory neurons as (i) decreases in action potential threshold, accommodation, and afterhyperpolarization, and (ii) increases in action potential duration, afterdischarge, and synaptic transmission. These alterations also occur, with a delay, after sensory axons are injured under condi...

DiCarlo, James J. and John H. R. Maunsell. Using neuronal latency to determine sensory–motor processing pathways in reaction time tasks. J Neurophysiol 93: 2974–2986, 2005. First published November 17, 2004; doi:10.1152/jn.00508.2004. We describe a new technique that uses the timing of neuronal and behavioral responses to explore the contributions of individual neurons to specific behaviors. Th...