to make an accurate estimation of the uptake of radioactivity in an organ using the conjugate view method, corrections of physical factors, such as background activity, scatter, and attenuation are needed. the aim of this study was to evaluate the accuracy of four different methods for background correction in activity quantification of the heart in myocardial perfusion scans. the organ activit...

The In-Stent Restenosis 2D model is a full y coupled multiscale simulation of post-stenting tissue growth, in which the most costly submodel blood flow simulation. This paper presents uncertainty estimations response this model, as obtained by both non-intrusive and semi-intrusive quantification. A surrogate based on Gaussian process regression for quantification takes whole black-box maps dire...

To improve the safety, reliability, and performance of complex engineering systems, it is crucial to understand quantify uncertainties. This paper presents a framework non-intrusively semi-analytically parametric uncertainty within CFD simulations using Bayesian quadrature (BQ). An in-house quantification (UQ) code based upon this mathematical developed. The then validated by applying due varyi...

We present a new data-driven model to reconstruct nonlinear flow from spatially sparse observations. The is version of conditional variational auto-encoder (CVAE), which allows for probabilistic reconstruction and thus uncertainty quantification the prediction. show that in our model, conditioning on measurements complete data leads CVAE where only decoder depends measurements. For this reason ...

pregabalin (prg) is a new antiepileptic drug and aceclofenac (ace) is a potent non-steroidal anti-inflammatory drug. these drugs in combination are used for treatment of partial seizures and neuropathic pains. a simple and precise assay method by rp-hplc was developed and validated for estimation of prg and ace in acenac-n tablet. analyses of commercial tablet, acenac-n were performed using jas...

Quantification of protein expression based on immunohistochemistry (IHC) is an important step for translational research and clinical routine. Several manual ('eyeballing') scoring systems are used in order to semi-quantify protein expression based on chromogenic intensities and distribution patterns. However, manual scoring systems are time-consuming and subject to significant intra- and inter...