BACKGROUND Besides the well-known adverse effects of valproate (VPA), disorders related to male reproductive functions have been reported. Furthermore, only a limited number of previous studies have reported the relationship between VPA dose and impairment of the hormonal axis and semen quality. A patient with reversible changes that occurred in the sperm parameters after a dose increment of VP...

The first pregnancy achieved in a seronegative woman following in-vitro fecundation through intracytoplasmic sperm (ICSI) injection from a man with autoimmune deficiency syndrome (AIDS; HIV-1 carrier) is reported. The semen was prepared by PureSperm and swim-up techniques. Some of the motile spermatozoa obtained were used to detect the presence of HIV-1 using the polymerase chain reaction techn...

Background: Oligoasthenospermia (OAS) is a condition characterized by low sperm count associated with low sperm motility. Medical treatment is not known in allopathic system for treatment of oligoasthenospermia. Homeopathic medicine is effective in more than 95% patients. Oxidative stress and decreased antioxidant levels have been projected as a potential factors involved in the pathophysiology...

The use of artificial insemination (AI) in buffalo (Bubalus bubalis) is limited by poor ovarian activity during the hot season, seasonal qualitative patterns in semen, low resistance of sperm cells in the female tract, difficulties in estrus detection, and variable estrus duration. Although AI procedures are commonly used in bovine, use of AI has been limited in buffalo. In the zootechnical fie...

In April 2016 ZIKA virus RNA was detected during control before performing in vitro fertilization in adult-man semen that contracted the infection in French Guyana and travel back to France. The infection had been detectable in the sperm by qRT-PCR and the virus persists in the semen even after routinely ART sperm migration performed in a bilayer gradient. Zika virus (ZIKV) is an arbovirus tran...

The aim of this pilot study was to establish a reactive oxygen species (ROS) evaluation method as a step in the routine diagnosis of men from infertile couples, which attend the Centre of Assisted Reproduction at the Teaching Hospital in Olomouc. Standard semen analyses were performed manually according to WHO guidelines. The number of peroxidase-positive leukocytes in the semen was determined ...

BACKGROUND Our understanding of early post-vasectomy recanalization is limited to histopathological studies. The objective of this study was to estimate the frequency and to describe semen analysis patterns of early recanalization after vasectomy. METHODS Charts displaying serial post-vasectomy semen analyses were created using the semen analysis results from 826 and 389 men participating in ...

BACKGROUND Recent progress in the treatment of sickle cell disease, in particular the use of hydroxyurea, has considerably modified the prognosis of this disease. Many more patients now reach reproductive age. The objective of this study was to assess the potential impact of hydroxyurea on the semen of patients. DESIGN AND METHODS In this retrospective multicenter study, we evaluated the sper...

OBJECTIVE The aim of this study was to evaluate the influence of different periods of abstinence on conventional semen parameters as well as functional parameters in human semen, including mitochondrial function, chromatin packing and sperm DNA fragmentation. METHODS We recruited a cohort of 2,458 men undergoing infertility investigation. Semen analyses were performed according to WHO guideli...

........................................................................................................... 6 ORIGINAL ARTICLES ......................................................................................... 8 ABBREVIATIONS ................................................................................................. 9 INTRODUCTION .....................................................