نتایج جستجو برای: semaphorin 3a
تعداد نتایج: 13208 فیلتر نتایج به سال:
Differing Semaphorin 3A Concentrations Trigger Distinct Signaling Mechanisms in Growth Cone Collapse
Semaphorin 3A Elicits Stage-Dependent Collapse, Turning, and Branching inXenopusRetinal Growth Cones
The neural scar that forms after injury to the mammalian central nervous system is a barrier to sprouting and regenerating axons. In addition to reactive astrocytes that are present throughout the lesion site, leptomeningeal fibroblasts invade the lesion core. When isolated in vitro, these cells form a very poor substrate for growing neurites, even more so than reactive astrocytes. Nevertheless...
OBJECTIVE Pathological retinal angiogenesis is a major cause of vision loss. Semaphorin 3A (Sema3A), a chemorepellent guidance protein, plays crucial roles in neural and vascular patterning. To identify its role in retinal neovascularization, we investigated its antiangiogenic effects. METHODS Human umbilical vein endothelial cells (HUVECs) were used for the in vitro study, and an oxygen-indu...
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