| October 2013 | 922 much attention has been made toward kidney protective efficiency of selenium. The results of the study conducted by Randjelovic et al., showed selenium supplementation attenuates oxidative-stress-associated renal injury by reducing oxygen free radicals and lipid peroxidation in gentamicin-treated rats,[4] while gentamicin-renal damage in Wistar rats is a model of acute kidn...

Interest in the chemopreventive effects of the trace element selenium has spanned the past three decades. Of >100 studies that have investigated the effects of selenium in carcinogen-exposed animals, two-thirds have observed a reduction in tumor incidence and/or preneoplastic endpoints (G. F. Combs and S. B. Combs, The Role of Selenium in Nutrition Chapter 10, pp. 413-462. San Diego, CA: Academ...

The aim of this study was to evaluate the influence of arsenic and bromine exposure with or without iodine and selenium supplementation on the element level in the thyroid of rats. Four major groups of Wistar female rats were fed with respective diets: group A - standard diet, group B - iodine rich diet (10 mg I/kg food), group C - selenium rich diet (1 mg Se/kg) and group D - iodine and seleni...

BACKGROUND This review is the third update of the Cochrane review "Selenium for preventing cancer". Selenium is a naturally occurring element with both nutritional and toxicological properties. Higher selenium exposure and selenium supplements have been suggested to protect against several types of cancer. OBJECTIVES To gather and present evidence needed to address two research questions:1. W...

the aim of this study was to evaluate the effect of organic selenium supplementation on the immune response of broilers vaccinated against coccidiosis, infection bursal disease virus (ibdv) and newcastle diseases virus (ndv). the study included three treatments (t), t1= control (inclusion of inorganic selenium in a basal diet), t2= basal diet + 0.2 ppm of organic selenium as selenomethionine an...

BACKGROUND The authors review the role of selenium and highlight possible low selenium levels in soil that may result in deficient states in Saudi Arabia. CASE PRESENTATION The authors report a case of selenium-responsive cardiomyopathy in a 15-month old Saudi Arabian boy. This case of selenium deficiency causing dilated cardiomyopathy is presented with failure to thrive, prolonged fever and ...

BACKGROUND Children are at particular risk for selenium deficiency, which has potentially serious medical implications. Reliable age-specific reference values for serum selenium concentrations in children are sparse, but are essential for the identification of selenium deficiency and decisions regarding selenium supplementation. METHODS Using electrothermal atomic absorption spectrometry, we ...

the effect of selenium yeast (SelPlexTM) as dietary organic selenium supplementation on the productive, reproductive and physiological traits of Bandarah local chickens from 40 to 60 weeks of age was studied. One hundred and sixty females and forty males at 40 weeks of age were distributed randomly among four treatment groups (40 females and 10 males in each group). Females and males were fed o...

Studies of dietary supplementation and cancer risk are full of surprises. Ten years ago, most epidemiologists and nutritionists sincerely believed that fl-carotene was the leading candidate for evaluation in chemoprevention trials. We now know that (3-carotene supplementation among smokers increases the risks of lung cancer, cardiovascular disease, and total mortality (1, 2). Although the story...

Earlier animal experiments have shown that selenium depletion may decrease immune functions. In this human study, 40 volunteers from a population with low serum selenium concentrations were supplemented with selenium or placebo for 11 weeks. Blood samples were drawn at intervals for analysis of selenium status and immune function. At the end of the supplementation period, plasma selenium levels...